The TGF-β Family
Author(s)
Bibliographic Information
The TGF-β Family
（Cold Spring Harbor monograph series, 50）
Cold Spring Harbor Laboratory Press, c2008
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Note
Includes bibliographical references and index
Description and Table of Contents
Description
TGF- b2; is the prototype of a protein superfamily which, in humans, contains at least 35 members, including activins, inhibins, bone morphogenetic proteins, growth/differentiation factors, and M fc;llerian inhibiting substance. This monograph draws on the world's leading laboratories to comprehensively cover all aspects of the biology of TGF- b2; and serve as a reference work for both specialists and researchers less familiar with the field.
Table of Contents
- Preface Foreword M.B. Sporn 1. The Discovery of TGF- b2
- : A Historical Perspective H.L. Moses and A.B. Roberts 2. TGF- b2
- and the TGF- b2
- Family R. Derynck and M. Miyazono CELL BIOLOGY 3. TGF- b2
- : A Multipotential Cytokine S.H. Schilling, A.B. Hjelmeland, J.N. Rich, and X.-F. Wang 4. Activins and Inhibins E. Wiater and W. Vale 5. The Bone Morphogenetic Proteins T. Katagiri, T. Suda, and K. Miyazono SIGNALING 6. Signaling Receptors of the TGF- b2
- Family J.L. Wrana, B. Ozdamar, C. Le Roy, and H. Benchabane 7. TGF- b2
- Bioavailability: Latency, Targeting, and Activation B. Dabovic and D.B. Rifkin 8. Agonists and Antagonists of the TGF- b2
- Family Ligands C. Chang 9. TGF- b2
- Signaling from Receptors to Smads C.-H. Heldin 10. Transcriptional Control via Smads X. Lin, Y.-G. Chen, and X.-H. Feng 11. Growth Control by TGF- b2
- : Mechanisms Controlling Cell Cycle Progression and Apoptosis P.M. Siegel and J. Massagu e9
- 12. Regulation of TGF- b2
- Family Signaling by Inhibitory Smads K. Miyazono 13. Structural Basis for TGF- b2
- Family Receptor Assembly and Signaling Specificity K. Lin and S. Choe 14. Non-Smad TGF- b2
- Signaling Pathways Y.E. Zhang 15. Regulation of the Smad Pathway by Signaling Cross-Talk K. Luo DIFFERENTIATION, DEVELOPMENT, AND PHYSIOLOGY 16. TGF- b2
- Family Signaling in Early Postimplantation Development of the Mouse S. Miura, M. Whitman, and Y. Mishina 17. TGF- b2
- Family Signaling in Drosophila G. Pyrowolakis, B. Hartmann, and M. Affolter 18. TGF- b2
- Signaling in the Nematode C. elegans G.I. Patterson and R.W. Padgett 19. TGF- b2
- Family Signaling in Xenopus and Zebrafish Embryos M. Whitman 20. TGF- b2
- Family Signaling in Stem Cell Renewal and Differentiation T. Watabe and K. Miyazono 21. TGF- b2
- Family Signaling in Mesenchymal Differentiation R. Derynck, E. Piek, R.A. Schneider, L. Choy, and T. Alliston 22. TGF- b2
- Family Signaling in Skeletal Development, Maintenance, and Disease T. Alliston, E. Piek, and R. Derynck 23. TGF- b2
- Family in Epithelial Development N.M. Mu f1
- oz and W.M. Grady 24. The TGF- b2
- Family in Endothelial Cell Differentiation and Cardiovascular Development and Function M.-J. Goumans, R. Carvalho, C. Mummery, and P. ten Dijke 25. TGF- b2
- as a Regulator of Myeloid and Lymphoid Development and Function J.J. Letterio and F.W. Ruscetti 26. The TGF- b2
- Family in Neural and Neuronal Differentiation and Development J. Samanta, M.A. Bonaguidi, and J.A. Kessler 27. The TGF- b2
- Family in the Reproductive Tract S.A. Pangas and M.M. Matzuk CANCER AND DISEASE 28. TGF- b2
- Signaling Pathway and Tumor Suppression W.M. Grady and S.D. Markowitz 29. TGF- b2
- Signaling in Epithelial-Mesenchymal Transition and Invasion and Metastasis R.J. Akhurst 30. TGF- b2
- and the Tumor Microenvironment B. Bierie and H.L. Moses 31. TGF- b2
- and Fibrosis E.P. B f6
- ttinger 32. Development of TGF- b2
- -based Therapeutic Agents: Capitalizing on TGF- b2
- 's Mechanisms of Action and Signal Transduction Pathways C.L. Arteaga and J.M. McPherson 33. BMP-based Therapeutics and the BMP Signaling Pathways G. Bain, A.J. Celeste, and J.M. Wozney Index
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