Power laws, scale-free networks and genome biology
著者
書誌事項
Power laws, scale-free networks and genome biology
（Molecular biology intelligence unit）
Landes Bioscience/Eurekah.com , Springer Science+Business Media, c2006
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注記
Includes bibliographical references and index
収録内容
- Power laws in biological networks / Eivind Almaas and Albert-László Barabási
- Graphical analysis of biocomplex networks and transport phenomena / Kwang-Il Goh, Byungnam Kahng and Doochul Kim
- Large-scale topological properties of molecular networks / Sergei Maslov and Kim Sneppen
- The connectivity of large genetic networks: design, history, or mere chemistry? / Andreas Wagner
- The drosophila protein interaction network may be neither power-law nor scale-free / J.S. Bader
- Birth and death models of genome evolution / Georgy P. Karev, Yuri I. Wolf and Eugene V. Koonin
- Scale-free evolution : from proteins to organisms / Nikolay V. Dokholyan and Eugene I. Shakhnovich
- Gene regulatory networks / T. Gregory Dewey and David J. Galas
- Power law correlations in DNA sequences / Sergey V. Buldyrev
- Analytical evolutionary model for protein fold occurrence in genomes, accounting for the effects of gene duplication, deletion, acquisition and selective pressure / Michael Kamal ... [et al.]
- The protein universes : some informatic issues in protein classification / S. Rackovsky
- The role of computation in complex regulatory networks / Pau Fernández and Ricard V. Solé
- Neutrality and selection in the evolution of gene families / Itai Yanai
- Scaling laws in the functional content of genomes : fundamental constants of evolution? / Erik van Nimwegen
内容説明・目次
内容説明
Power Laws, Scale-free Networks and Genome Biology deals with crucial aspects of the theoretical foundations of systems biology, namely power law distributions and scale-free networks which have emerged as the hallmarks of biological organization in the post-genomic era. The chapters in the book not only describe the interesting mathematical properties of biological networks but moves beyond phenomenology, toward models of evolution capable of explaining the emergence of these features. The collection of chapters, contributed by both physicists and biologists, strives to address the problems in this field in a rigorous but not excessively mathematical manner and to represent different viewpoints, which is crucial in this emerging discipline. Each chapter includes, in addition to technical descriptions of properties of biological networks and evolutionary models, a more general and accessible introduction to the respective problems. Most chapters emphasize the potential of theoretical systems biology for discovery of new biological phenomena.
目次
Power Laws in Biological Networks.- Graphical Analysis of Biocomplex Networks and Transport Phenomena.- Large-Scale Topological Properties of Molecular Networks.- The Connectivity of Large Genetic Networks.- The Drosophila Protein Interaction Network May Be neither Power-Law nor Scale-Free.- Birth and Death Models of Genome Evolution.- Scale-Free Evolution.- Gene Regulatory Networks.- Power Law Correlations in DNA Sequences.- Analytical Evolutionary Model for Protein Fold Occurrence in Genomes, Accounting for the Effects of Gene Duplication, Deletion, Acquisition and Selective Pressure.- The Protein Universes.- The Role of Computation in Complex Regulatory Networks.- Neutrality and Selection in the Evolution of Gene Families.- Scaling Laws in the Functional Content of Genomes.
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