The relationship between coagulation, inflammation and endothelium : a pyramid towards outcome
著者
書誌事項
The relationship between coagulation, inflammation and endothelium : a pyramid towards outcome
（A Society of Cardiovascular Anesthesiologists monograph）
Lippincott Williams & Wilkins, c2000
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注記
Includes bibliographical references and index
内容説明・目次
内容説明
Cardiopulmonary bypass (CPB) creates profound changes throughout every organ system in the body, resulting in an unacceptably high number of adverse outcomes, including myocardial infarction, stroke, neuropsychiatric defects, infection, pulmonary dysfunction, and perioperative bleeding. An understanding of the deviations of homeostasis caused by CPB is needed to minimize the frequency of these adverse effects. Rather than examining the vascular endothelium, inflammation, and coagulation "systems" as distinct, this monograph examines the interactions between these three facets of the circulatory system. It is in these interactions that solutions may be found to the problems that lead to the adverse outcomes of CPB. This monograph also focuses on the complex interactions of vascular homeostasis and how individual reactivity might well drive outcomes. How severely homeostatic control is shaken by CPB greatly affects how a patient does during surgery. This book examines the research that embraces and understands this variability of response and looks to possible future developments that may help clinicians predict how individuals might react to the homeostatic insult that is CPB
目次
The Evolution of Coagulation and InflammationThe Endothelium at RestThe Endothelium Disturbed: The Procoagulant Responsethe Relationships Between Coagulation, Inflammation and Endothelium: Inflammation RespondsPlatelets and their InteractionsA Contemporary View of CoagulationThe Fibrinolytic Response during Cardiopulmonary Bypass - Pro or Anticoagulant? Heparin: Beyond an AngicoagulantCoagulation and Inflammation Polymorphism: Impact on Cardiovascular Outcomes .Inde
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