Breast cancer chemosensitivity
著者
書誌事項
Breast cancer chemosensitivity
(Advances in experimental medicine and biology, v. 608)
Springer Science+Business Media , Landes Bioscience, c2007
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注記
Includes bibliographical references and index
内容説明・目次
内容説明
In Breast Cancer Chemosensitivity, a group of world leading experts review critical aspects of resistance to systemic therapy in breast cancer patients. Beginning with a clinical overview of the problem, the book then focuses on the latest findings of molecular mechanisms of drug resistance. Coverage provides an example of using novel approaches for chemosensitization of breast cancer cells that gives readers an idea about the future direction in breast cancer treatment. It allows those who are interested in breast cancer therapy to get a jump-start on critical issues in breast cancer therapeutic resistance.
目次
Overview of Resistance to Systemic Therapy in Patients with Breast Cancer.- Roles of Multidrug Resistance Genes in Breast Cancer Chemoresistance.- Therapy-Induced Apoptosis in Primary Tumors.- Cell Cycle Deregulation in Breast Cancer: Insurmountable Chemoresistance or Achilles' Heel?.- p53, BRCA1 and Breast Cancer Chemoresistance.- Integrin-Mediated Adhesion: Tipping the Balance between Chemosensitivity and Chemoresistance.- Insulin-Like Growth Factors and Breast Cancer Therapy.- EGF Receptor in Breast Cancer Chemoresistance.- Molecular Mechanisms of ErbB2-Mediated Breast Cancer Chemoresistance.- Estrogen Receptors in Resistance to Hormone Therapy.- Novel Approaches for Chemosensitization of Breast Cancer Cells: The E1A Story.
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