Oxidative and nitrosative stress in redox regulation of cell signaling
Author(s)
Bibliographic Information
Oxidative and nitrosative stress in redox regulation of cell signaling
(Methods in enzymology / editors in chief, Sidney P. Colowick, Nathan O. Kaplan, v. 440-441 . Nitric oxide ; pt. F-G)
Elsevier Academic Press, c2008
- pt. F
- pt. G
Available at 51 libraries
  Aomori
  Iwate
  Miyagi
  Akita
  Yamagata
  Fukushima
  Ibaraki
  Tochigi
  Gunma
  Saitama
  Chiba
  Tokyo
  Kanagawa
  Niigata
  Toyama
  Ishikawa
  Fukui
  Yamanashi
  Nagano
  Gifu
  Shizuoka
  Aichi
  Mie
  Shiga
  Kyoto
  Osaka
  Hyogo
  Nara
  Wakayama
  Tottori
  Shimane
  Okayama
  Hiroshima
  Yamaguchi
  Tokushima
  Kagawa
  Ehime
  Kochi
  Fukuoka
  Saga
  Nagasaki
  Kumamoto
  Oita
  Miyazaki
  Kagoshima
  Okinawa
  Korea
  China
  Thailand
  United Kingdom
  Germany
  Switzerland
  France
  Belgium
  Netherlands
  Sweden
  Norway
  United States of America
Note
Includes bibliographical references and indexes
Description and Table of Contents
- Volume
-
pt. F ISBN 9780123739674
Description
The discovery that nitrogen monoxide or nitric oxide (NO)is a biologically produced free radical has revolutionized our thinking about physiological and pathological processes. This discovery has ignited enormous interest in the scientific community. When generated at low levels, NO is a signaling molecule, but at high concentration, NO is a cytotoxic molecule. The physiological and pathological processes of NO production and metabolism and its targets, currently areas of intensive research, have important pharmacologic implications for health and disease.
- Volume
-
pt. G ISBN 9780123743091
Description
The Nobel Prize was awarded in Physiology or Medicine in 1998 to Louis J. Ignarro, Robert F. Furchgott and Ferid Murad for demonstrating the signaling properties of nitric oxide. Nitric oxide (NO) is one of the few gaseous signaling molecules and is a key biological messenger that plays a role in many biological processes. NO research has led to new treatments for treating heart as well as lung diseases, shock and impotence. (Sildenafil, popularly known by the trade name Viagra, enhances signaling through NO pathways.) Scientists are currently testing whether NO can be used to stop the growth of cancerous tumors, since the gas can induce programmed cell death, apoptosis.
This is another "must-have" volume packed with robust methods from authors around the globe. Researchers interested in the detailed biochemistry of NO and its synthesis will have this indispensable volume on their shelves.
Table of Contents
Chapter One: Protein 3-Nitrotyrosine in Complex Biological Samples: Quantification by High-Pressure Liquid Chromatography/Electrochemical Detection and Emergence of Proteomic Approaches for Unbiased Identification of Modification Sites
Chapter Two: Selective Fluorogenic Derivatization of 3-Nitrotyrosine and 3,4-Dihydroxyphenylalanine in Peptides: A Method Designed for Quantitative Proteomic Analysis
Chapter Three: Nitroalkenes: Synthesis, Characterization, and Effects on Macrophage Activation
Chapter Four: In-Gel Detection of S-Nitrosated Proteins Using Fluorescence Methods
Chapter Five: The Arachidonate-Dependent Survival Signaling Preventing Toxicity in Monocytes/Macrophages Exposed to Peroxynitrite
Chapter Six: Practical Approaches to Investigate Redox Regulation of Heat Shock Protein Expression and Intracellular Glutathione Redox State
Chapter Seven: Monitoring Oxidative Stress in Vascular Endothelial Cells in Response to Fluid Shear Stress: From Biochemical Analyses to Micro- and Nanotechnologies
Chapter Eight: Determination of S-Nitrosothiols in Biological and Clinical Samples Using Electron Paramagnetic Resonance Spectrometry with Spin Trapping
Chapter Nine: Novel Method for Measuring S-Nitrosothiols Using Hydrogen Sulfide
Chapter Ten: Kinetic Studies on Peroxynitrite Reduction by Peroxiredoxins
Chapter Eleven: Nitrocytochrome c: Synthesis, Purification, and Functional Studies
Chapter Twelve: Tyrosine Nitration, Dimerization, and Hydroxylation by Peroxynitrite in Membranes as Studied by the Hydrophobic Probe N-T-BOC-L-tyrosine tert-Butyl Ester
Chapter Thirteen: Assessment of Superoxide Production and NADPH Oxidase Activity by HPLC Analysis of Dihydroethidium Oxidation Products
Chapter Fourteen: Methods to Measure the Reactivity of Peroxynitrite-Derived Oxidants Toward Reduced Fluoresceins and Rhodamines
Chapter Fifteen: Detection and Characterization of Peroxynitrite-Induced Modifications of Tyrosine, Tryptophan, and Methionine Residues by Tandem Mass Spectrometry
Chapter Sixteen: Reductive Gas-Phase Chemiluminescence and Flow Injection Analysis for Measurement of the Nitric Oxide Pool in Biological Matrices
Chapter Seventeen: Detection and Measurement for the Modification and Inactivation of Caspase by Nitrosative Stress In Vitro and In Vivo
Chapter Eighteen: Interactive Relations between Nitric Oxide (NO) and Carbon Monoxide (CO): Heme Oxygenase-1/CO Pathway Is a Key Modulator in NO-Mediated Antiapoptosis and Anti-inflammation
Chapter Nineteen: Detection and Characterization of In Vivo Nitration and Oxidation of Tryptophan Residues in Proteins
Chapter Twenty: In Vivo Real-Time Measurement of Nitric Oxide in Anesthetized Rat Brain
Chapter Twenty-One: Nitric Oxide and Cardiobiology-Methods for Intact Hearts and Isolated Myocytes
Chapter Twenty-Two: Microscopic Technique for the Detection of Nitric Oxide-Dependent Angiogenesis in an Animal Model
Author Index
Subject Index
by "Nielsen BookData"