Asymmetric organic synthesis with enzymes

書誌事項

Asymmetric organic synthesis with enzymes

edited by Vicente Gotor, Ignacio Alfonso, and Eduardo García-Urdiales

Wiley-VCH, c2008

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注記

Includes bibliographical references and index

内容説明・目次

内容説明

Perfect for biochemists, synthetic and organic chemists, this book covers all important reactions, including C-C coupling reactions, oxidation reactions and many more. Divided into two parts, the first section on methodology presents new innovative methods for enzymatic catalysis optimization, including such new trends as medium engineering, directed evolution and computer-aided prediction of enantioselectivity. The second and main section deals with applications to synthesis, showing important reaction types and their applications. Only those reactions with very high selectivity are presented, allowing readers to improve their own reaction yields.

目次

METHODOLOGY Medium Engineering: Directed evolution: The search for new enzymes: SYNTHETIC APPLICATIONS Dynamic Kinetic Resolutions: Deracemization and Enantioconvergent Processes: Transesterification and hydrolysis of carboxylic acid derivatives, alcohols and epoxides Aminolysis and ammonolysis of carboxylic acid derivatives: Reduction Reactions: Oxidation Reactions: Making and breaking C-C bonds:

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