The use of non-structural proteins of foot and mouth disease virus (FMDV) to differentiate between vaccinated and infected animals

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Bibliographic Information

The use of non-structural proteins of foot and mouth disease virus (FMDV) to differentiate between vaccinated and infected animals

(IAEA-TECDOC, 1546)

International Atomic Energy Agency, c2007

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Publication prepared under the framework of an RCA project with the technical support of the joint FAO/IAEA programme of nuclear techniques in food and agriculture

"May 2007"

Includes bibliographical references

Description and Table of Contents

Description

This publication contains important cumulative information on the development of tests to measure antibodies produced against foot and mouth disease virus (FMDV) and to differentiate animals infected with foot and mouth disease (FMD) from those only given vaccines. During the past decade there has been a constant development of tests to attempt this and claims that have not always been substantiated with data. An IAEA Coordinated Research Project (CRP) was undertaken to evaluate institutionally and then commercially derived tests to obtain validation data defining test performances from a wide geographical arena in laboratories of varying standards. The conclusions from the CRP, presented in this publication, will add value to the current debate on the usefulness of such tests.

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