Angiogenesis : in vitro systems
著者
書誌事項
Angiogenesis : in vitro systems
（Methods in enzymology / editors in chief, Sidney P. Colowick, Nathan O. Kaplan, v. 443）
Academic Press, c2008
大学図書館所蔵 全43件
注記
Includes bibliographical references and indexes
内容説明・目次
内容説明
Angiogenesis is the growth of new blood vessels and is an important natural process in the body. A healthy body maintains a perfect balance of angiogenesis modulators. In many serious disease states, however, the body loses control over antiogenesis. Diseases that are angiogensis-dependent result when blood vessels either grow excessively or insufficiently.
目次
- Studying cell signaling pathways
- Flow mediated signaling
- Endothelial cell adhesion and migration on the ECM
- EC sprouting assays
- Lumen formation assays
- Isolation and propagation of EC's or SMC's
- Cell-based assays to screen anti-angiogenic agents (chemical approach
- ES cell models of vascular network formation
- Co-culture studies with EC plus other cell types
- Aortic ring sprouting (multiple cell types present)
- Effects of hypoxia or hyperoxia
- Vascular Proteomics
- In vitro vascular barrier function
- EC leukocyte interactions
- ECM signaling to the vasculature
- Vascular Integrin signaling
- Mechanical Signaling in blood vessels
- Vascular and neuronal patterning
- Vascular growth factors and their signals
- VEGF receptor signal transduction
- Development and testing of monoclonal antibodies directed to angiogenic targets.
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