Dopamine research advances

著者

    • Watanabe, Akiyama

書誌事項

Dopamine research advances

Akiyama Watanabe, editor

Nova Biomedical Books, c2008

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注記

Includes bibliographical references and index

HTTP:URL=http://www.loc.gov/catdir/toc/ecip0720/2007024086.html Information=Table of contents only

内容説明・目次

内容説明

Dopamine is a phenethylamine naturally produced by the human body. In the brain, dopamine functions as a neurotransmitter, activating the five types of dopamine receptor -- D1, D2, D3, D4 and D5, and their variants. Dopamine is produced in several areas of the brain, including the substantia nigra. Dopamine is also a neurohormone released by the hypothalamus. Its main function as a hormone is to inhibit the release of prolactin from the anterior lobe of the pituitary. Dopamine can be supplied as a medication that acts on the sympathetic nervous system, producing effects such as increased heart rate and blood pressure. However, since dopamine cannot cross the blood-brain barrier, dopamine given as a drug does not directly affect the central nervous system. To increase the amount of dopamine in the brains of patients with diseases such as Parkinson's disease and Dopa-Responsive Dystonia, L-DOPA (levodopa), which is the precursor of dopamine, can be given because it can cross the blood-brain barrier. This book presents new research in the field.

目次

  • Preface
  • Dopamine Control of Sleep and Arousal
  • A Circuit Dynamics Theory of Complex Dopaminergic Modulation of Prefrontal Cortical Activity and its Relevance to Schizophrenia
  • The Life Cycle of the Dopaminergic Neurons in the Substantia Nigra
  • Electrophysiological and Neurochemical In Vivo Studies on Serotonin 5-HT 2C Control of Central Dopaminergic Function
  • Dopamine Effects on the Adrenal Gland of the Newt Triturus Carnifex (Amphibia, Urodela)
  • Serotonin 5-HT 2C Receptor and Dopamine Function in Depression
  • A Possible Role for Intracellular Pathways Activation in the Modulation of Learning and Memory Processes by the Dopaminergic and Opioid Systems Interaction
  • Dopamine System and its Modulation by Nitric Oxide: Approaches in Experimental Parkinson and Schizophrenia
  • Dopamine Receptors Regulation by Non-Dopaminergic Mechanisms
  • Index.

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