Systems biology
著者
書誌事項
Systems biology
（Essays in biochemistry, v. 45）
Portland Press, c2008
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注記
Includes bibliographical references and index
Series editor: Melanie Welham (U.K.)
内容説明・目次
内容説明
This book contains topics including modelling the dynamics of signalling pathways, modelling metabolic networks using power-laws and S-systems, modelling reaction kinetics in cells, the regulatory design of cellular processes, metabolomics and fluxomics, modelling cellular signalling systems, systems analysis of MAPK signal transduction, systems biology of JAK/STAT signalling, and single live-cell imaging for systems biology. The other topics include using thiamine uptake in yeast as a case study in systematic modelling, short-term volume and turgor regulation in yeast, network reconstruction based on steady-state data, sensitivity analysis, parameter estimation and optimal experimental design, standards and ontologies in computational systems biology, and systems biology model databases and resources.
目次
- Modelling the dynamics of signalling pathways
- Modelling metabolic networks using power-laws and S-systems
- Modelling reaction kinetics inside cells
- The harmony of the cell: the regulatory design of cellular processes
- Metabolomics and fluxomics approaches
- Modelling cellular signalling systems
- Systems analysis of MAPK signal transduction
- Systems biology of JAK/STAT signalling
- Single live-cell imaging for systems biology
- Case study in systematic modelling: thiamine uptake in the yeast Saccharomyces cerevisiae
- Short-term volume and turgor regulation in yeast
- Network reconstruction based on steady-state data
- Sensitivity analysis: from model parameters to system behaviour
- Parameter estimation and optimal experimental design
- Standards and ontologies in computational systems biology
- Systems biology model databases and resources
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