Origin and evolution of viruses

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Origin and evolution of viruses

edited by Esteban Domingo, Colin R. Parrish, John J. Holland

Elsevier Academic Press, 2008

2nd ed

Available at  / 8 libraries

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Includes bibliographical references and index

Description and Table of Contents

Description

New viral diseases are emerging continuously. Viruses adapt to new environments at astounding rates. Genetic variability of viruses jeopardizes vaccine efficacy. For many viruses mutants resistant to antiviral agents or host immune responses arise readily, for example, with HIV and influenza. These variations are all of utmost importance for human and animal health as they have prevented us from controlling these epidemic pathogens. This book focuses on the mechanisms that viruses use to evolve, survive and cause disease in their hosts. Covering human, animal, plant and bacterial viruses, it provides both the basic foundations for the evolutionary dynamics of viruses and specific examples of emerging diseases.

Table of Contents

1. Early Replication: Origin and Evolution 2. Structure and Evolution of Viroids 3. Mutation, Competition and Selection as Measured with Small RNA Molecules 4. Viral Quasispecies: Dynamics, Interactions and Pathogenesis 5. Comparative Studies of RNA Virus Evolution 6. Nucleic Acid Polymerase Fidelity and Viral Population Fitness 7. The complex Interactions of Viruses and the RNAi Machinery: A Driving Force in Viral Evolution 8. The Role of the APOBEC3 Family of Cytidine Deaminases in Innate Immunity, G-to-A Hypermutation 9. Lethal Mutagenesis 10. Evolution of dsDNA Tailed Phages 11. More about Plant Virus Evolution - Past, Present and Future 12. Mutant clouds and bottleneck events in plant virus evolution 13. Retrovirus Evolution 14. Intra-host dynamics and evolution of HIV Infection 15. The Impact of Rapid Evolution of Hepatitis Viruses 16. Arbovirus Evolution 17. Evolution and Variation of the Parvoviruses 18. Genome Diversity and Evolution of Papillomaviruses 19. Origin and Evolution of Poxviruses 20. Molecular Evolution of the Herpesvirales 21. The widespread evolutional significance of viruses

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