Principles of bone biology

著者

書誌事項

Principles of bone biology

edited by John P. Bilezikian, Lawrence G. Raisz, T. John Martin

Academic, c2008

3rd ed

  • : set
  • v. 1
  • v. 2

大学図書館所蔵 件 / 全27件

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注記

Includes bibliographical references and index

内容説明・目次

内容説明

Principles of Bone Biology provides the most comprehensive, authoritative reference on the study of bone biology and related diseases. It is the essential resource for anyone involved in the study of bone biology. Bone research in recent years has generated enormous attention, mainly because of the broad public health implications of osteoporosis and related bone disorders.

目次

Part I Basic Principles A. Cell Biology 1: Structure, Modeling and Remodeling of Bone / The Size and Shape of Bone as a Site of Metabolic Bone Activity 2: Biomechanics of Bone 3: Embryonic Development of Bone and the Molecular Regulation of Intramembranous and Endochondral Bone Formation 4: Mesenchymal Stem Cells & Osteoblast Lineage 5: Transcriptional Control of Osteoblast Differentiation and Function 6: Wnt Signaling and Bone 7: Sclerostin and Bone 8: The Osteocyte 9: Cells of Bone: Osteoplast Generation 10: Osteoclast Function: Biology and Mechanisms 11: RANK Signaling 12: Regulating Bone Resorption 13: Apoptosis in Bone Cells 14: Skeletal Gene Expression in Nuclear Microenvironments B. Biochemistry 15: Type I Collagen: Structure, Synthesis, and Regulation 16: Collagen Crosslinking & Metabolism 17: Bone Matrix Proteoglycans & Glycoproteins 18: Osteopontin 19: Bone Proteinases 20: Integrins and Other Cell Surface Attachment Molecules of Bone Cells 21: Intercellular Junctions and Cell-Cell Communication in the Skeletal System C. Bone Remodeling and Mineral Homeostasis 22: Histomorphometric Analysis of Bone Remodeling 23: Phosphorus Homeostasis & Related Disorders 24: Magnesium Homeostasis 25: Metals in Bone: Aluminum, Boron, Cadmium, Chromium, Lead, Silicon, & Stro 26: Biology of the Extracellular Ca2+-Sensing Receptor D. The Hormones of Bone 27: Receptors for Parathyroid Hormone (PTH) and PTH-Related Protein 28: Parathyroid Hormone - Molecular Biology 29: Parathyroid Hormone-Receptor Interactions 30: Actions of Parathyroid Hormone on the Vasculature and Cardiovascular System 31: The Vascular and Cardiovascular Actions of PTH 32: PTH and PTHrP Actions on Kidney and Bone 33: Physiological Actions of Parathyroid Hormone and PTH-Related Protein 34: Vascular, Cardiovascular and Neurological Actions of Parathyroid-Related Protein 35: Vitamin D Nuclear Receptor (VDR) and Plasma Vitamin D-Binding Protein (DBP) Structures and Ligand Shape Preferences for Genomic and Rapid Biological Responses 36: Vitamin D Gene Regulation 37: Photobiology and Non-Calcemic Actions of Vitamin D 38: Calcitonin Structure and Molecular Biology of the Calcitonin Receptor / Calcitonin Gene Family and Receptors: Structure, Molecular Biology, and Effects 39: Amylin and Calcitonin Gene-Related Peptide E. Other Systemic Hormones That Influence Bone Metabolism 40: Estrogens & Progestins 41: The Pharmacology of Selective Estrogen Receptor Modulators 42: Mechanisms of Estrogen Action in Bone 43: Thyroid Hormone & Bone 44: Clinical and Basic Aspects of Glucocorticoid Action in Bone 45: Effects of Diabetetes & Insulin on Bone Physiology 46: Androgens:Receptor Expression and Steroid Action in Bone 47: Kinins & Neuro-Osteogenic Factors 48: Regulation of Bone Remodeling by Central and Peripheral Nervous Signals Patricia Ducy F. Local Regulators 49: Insulin-like Growth Factors and the IGF Binding Proteins: Implications for Bone Biology 50: Platelet-Derived Growth Factor & the Skeleton 51: Fibroblast Growth Factor (FGF) and FGF Receptor Families in Bone 52: Vascular Endothelial Growth Factor and Osteogenic-Angiogenic Coupling 53: Transforming Growth Factor-a 54: Bone Morphogenetic Proteins and the Skeleton 55: Bone Morphogenetic Protein Receptors & Actions 56: Colony-Stimulating Factor-1 57: Local Regulators of Bone: IL-1, TNF, Lymphotoxin, Interferon-?, IL-8, IL-10, IL-4, the LIF/IL-6 Family, and Additional Cytokines 58: Prostaglandins & Bone Metabolism Carol Pilbeam Part II Molecular Mechanisms of Metabolic Bone Disease 59: Skeletal Effects of Nitric Oxide: Novel Agent for Osteoporosis 60: Molecular Basis of PTH Overexpression 61: Familial Benign Hypocalciuric Hypercalcemia and Neonatal Primary Hyperparathyroidism 62: Multiple Endocrine Neoplasia Type I 63: Parathyroid Hormone-Related Peptide and Other Systemic Factors in Skeletal Manifestations of Malignancy 64: Local Factors in Skeletal Malignancy 65: Genetic Regulation of the Parathyroid Gland Development 66: Jansen's Metaphyseal Chondrodysplasia & Blomstrand's Lethal Chondrodysplasia: Two Genetic Disorders Caused by PTH/PTHrP Receptor Mutations 67: Diseases Resulting from Defects in the G Protein Gs 68: Renal Osteodystrophy - Pathogenic Mechanisms and Therapeutic Options 69: Osteogenesis Imperfecta 70: Hereditary Deficiencies in Vitamin D Action 71: Oncogenic Osteomalacia 72: Osteopetrosis 73: Hypophosphatasia: Nature's Window on Alkaline Phosphatase Function in Humans 74: Paget's Disease of Bone 75: Genetic Determinants of Bone Mass and Osteoporotic Fracture 76: Pathophysiology of Osteoporosis 77: Evaluation of Risk for Osteoporosis Fracture Part III Pharmacological Mechanisms of Therapeutics 78: Parathyroid Hormone 79: Calcium 80: Drugs Acting on the Calcium Receptor Calcimimetics and Calcilytics 81: Bisphosphonates: Mechanisms of Action 82: The Pharmacology of Estrogens in Osteoporosis 83: Vitamin D & Analogs 84: Estrogen Effects on Bone in the Male Skeleton 85: Mechanisms of Exercise Effects on Bone Quantity and Quality Part IV Methods in Bone Research 86: Application of Transgenic Mice to Problems of Skeletal Bone 87: Biochemical Markers of Bone Metabolism 88: Methods and Clinical Issues in Bone Densitometry 89: Controversial Issues in Bone Densitometry 90: Macro and Micro Imaging of Bone Architecture

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