The importance of polymer science for biological systems : University of York, UK, 26-28 March 2008
著者
書誌事項
The importance of polymer science for biological systems : University of York, UK, 26-28 March 2008
（Faraday discussions, v. 139）
RSC, c2008
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注記
"A General Discussion on the Importance of Polymer Science for Biological Systems was held at the University of York, UK on 26th, 27th and 28th March 2008"--Contents
"The Faraday Division of the Royal Society of Chemistry"--T.p. verso
Includes bibliographical references and index
内容説明・目次
内容説明
Key molecules in biological systems are polymers: proteins, polysaccharides and the nucleic acids. Their long chain behaviour is a crucial contributing factor to their function in living systems. The fundamental motif of cells - membranes that separate space into multicompartments - has an analogy with polymeric amphiphiles, their slow dynamics allowing access to both kinetic insights and tougher membranes. There is increasing dialogue between the different communities of polymer scientists and biologists/clinicians, reflecting the growing awareness that only by bringing together interdisciplinary ideas will fast progress be made. The meeting will aim to focus on two main strands: the physical chemistry of macromolecules as common ground between biology and polymer science; and the problems associated with biocompatibility and biodegradability of polymers, particularly with regard to their role as therapeutic delivery vehicles. Themes of the meeting will include: Cells and membranes Self assembly processes, Signalling pathways, Molecular motors, Dynamics, Drug delivery, Tissue scaffolds, Novel biomaterials.
目次
Session 1: Cell Interactions Phase separation of equilibrium polymers of proteins in living cells Internal friction of polypeptide chains at high stretch Quantifying the relation between bond number and myoblast proliferation Thermo-reversible protein fibrillar hydrogels as cell scaffolds The polymer physics and chemistry of microbial cell attachment and adhesion Session 2: Membranes and Walls Leuko-polymersomes Non-cytotoxic polymer vesicles for rapid and efficient intracellular delivery Mixed protein-polysaccharide interfacial layers: A self consistent field calculation study Calcium phosphate mineralization beneath monolayers of poly(n-butyl acrylate)-block-poly(acrylic acid) block copolymers Probing (macro)molecular transport through cell walls Session 3:Proteins and Polysaccharides Fibronectin in aging extracellular matrix fibrils is progressively unfolded by cells and elicits an enhanced rigidity response Correlations between structure, material properties and bioproperties in self-assembled beta-hairpin peptide hydrogels Common motifs in protein self-assembly Cellulose fibrils direct plant organ movements Molecular and crystal deformation of cellulose: uniform strain or uniform stress? Protein crystallization: universal thermodynamic vs specific aspects of PEG Session 4: Natural and Synthetic Polymers Incorporating stimulus-responsive character into filamentous virus assemblies The viscoelasticity of self-assembled proteoglycan combs Synthesis of well-defined glycopolymers and some studies of their aqueous solution behaviour Spontaneous flow of active polar gels in undulated channels Effect of confinement on properties of stiff biological macromolecules Marine biopolymer self-assembly: implications for carbon cycling in the ocean
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