Neocortical modularity and the cell minicolumn
著者
書誌事項
Neocortical modularity and the cell minicolumn
Nova Biomedical Books, c2005
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注記
Includes bibliographical references and index
内容説明・目次
内容説明
Our everyday view of the world may not necessarily be the most comprehensive one. In this regard neuropathologists should temper opinions based on a limited representation of reality. Microscopy freezes in time a two-dimensional representation of a minute histological process. One must acquire knowledge of the physiology of the lesion before reaching a multidimensional diagnosis. In the case of mental disorders, the modular organisation of the cortex may offer some clues to underlying aetiology. It is tissue, rather than individual cells, that provides for the phenomena of perceptual binding and gamma frequencies. It is the continuous re-entry of excitation into neuronal networks that provides for selective attention. The basis for language and its semantic content resides in the conjoint activation of topographically diverse brain regions. This book is designed to focus on the lowest hierarchical element within the modular organisation of the brain: the cell minicolumn. The minicolumn is a self-contained ecosystem of neurons and their connections that repeats itself throughout the extent of the neocortex. Although a few neuroanatomists at the turn of the century called attention to the vertical arrangement of the cortex, Vernon Mountcastle provided physiological proof in the 1950's for its existence and its role in perception.
目次
- Acknowledgement
- Introduction
- A Life that Transformed the Neurosciences
- Scientific Achievements
- An Apologia for a Paradigm Shift in the Neurosciences
- Reflections on the Structure of the Cortical Minicolumn
- The Cell Column in Comparative Anatomy
- Encephalisation, Minicolumns, and Hominid Evolution
- The Generation and Migration of Cortical Interneurons
- Minicolumnar Patterns in the Global Cortical Response to Sensory Stimulation
- Minicolumnar Morphometry: Computerised Image Analysis
- The Verticality Index: A Quantitative Approach to the Analysis of the Columnar Arrangement of Neurons in the Primate Neocortex
- Mountcastle Principle of Columnar Cortex as a Basis for the Theory of Higher Brain Function: Clinical Relevance
- Index.
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