Bibliographic Information

Methods for neural ensemble recordings

edited by Miguel A.L. Nicolelis

(Frontiers in neuroscience / editors, Sidney A. Simon, Miguel A. L. Nicolelis)

CRC Press, c2008

2nd ed

  • : hardcover

Available at  / 6 libraries

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Includes bibliographical references and index

Description and Table of Contents

Description

In the last ten years neural ensemble recording grew into a well-respected and highly data-lucrative science. New experimental paradigms, including the fabrication of high-density microelectrodes, new surgical implantation techniques, multi-channel signal processing, and the establishment of direct real-time brain-machine interfaces, hold promise not just for neurophysiology research, but also for new-generation prosthetic devices aimed at restoring mobility and communication skills in severely disabled patients. Extensively updated and expanded, Methods for Neural Ensemble Recording, Second Edition distills the current state-of-the-science and provides the nuts and bolts foundation from which to advance the field for the next ten years. With contributions from pioneering researchers, this second edition begins with an overview of microwire array design for chronic neural recordings. Demonstrating the diversity now enjoyed in the field, the book reviews new surgical techniques for chronic implantation of microwire arrays in not just rodents, but primates as well. It explores microelectrode microstimulation of brain tissue, discusses multielectrode recordings in the somatosensory system and during learning, and analyzes neural ensemble recordings from the central gustatory-reward pathways in awake and behaving animals. An exploration of new strategies for neural ensemble data analysis for Brain-Machine Interface (BMI) applications foreshadows an investigation into employing BMI to restore neurological function. Using multielectrode field potential recordings, contributions define global brain states and propose conceptual and technical approaches to human neural ensemble recordings in the future.

Table of Contents

State-of-the-Art Microwire Array Design for Chronic Neural Recordings in Behaving Animals. Surgical Techniques for Chronic Implantation of Microwire Arrays in Rodents and Primates. Technology for Multielectrode MicroStimulation of Brain Tissue. Strategies for Neural Ensemble Data Analysis for Brain-Machine Interface (BMI) Applications. Chronic Recordings in Transgenic Mice. Multielectrode Recordings in the Somatosensory System. Chronic Recording during Learning. Defining Global Brain States using Multielectrode Field Potential Recordings. Multielectrode Recording in Behaving Monkeys. Neural Ensemble Recordings from Central Gustatory-Reward Pathways in Awake and Behaving Animals. Building Brain-Machine Interfaces to Restore Neurological Functions. Conceptual and Technical Approaches to Human Neural Ensemble Recordings. Index.

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