Mouse models of developmental genetic disease

著者

• Krauss, Robert S.

書誌事項

Mouse models of developmental genetic disease

edited by Robert S. Krauss

（Current topics in developmental biology / edited by A.A. Moscona, Alberto Monroy, v. 84）

Academic, 2008

1st ed

注記

Includes bibliographical references and index

内容説明・目次

内容説明

Approximately three percent of newborn humans have congenital anomalies with significant cosmetic and/or functional consequences. Much of our ability to understand what has gone awry in these birth defects rests with development of animal models for them; the mouse has emerged as the model organism of choice for these studies. This volume reviews mouse models of specific developmental genetic diseases, including neural tube defects; cleft lip and/or palate; congenital heart disease; ciliopathies; hereditary deafness and others to provide conceptual insight into congenital anomalies generally. The interplay between clinical observation and murine model systems is expected to yield deep insight into mammalian developmental processes and the emergence of effective preventive and/or therapeutic strategies.

目次

1) Comprehensive Phenotyping of Genetically Modified Mice to Identify New Target Disease Indications Author: Sandra Engle 2) Modeling the Repair Process in Multiple Sclerosis Author: H. Arnett 3) Mouse Genetic Models for Individualized Symptomatology of Cancer and Infectious Disease Author: P. Demant 4) New Rodent Models for Obesity, Diabetes, and Metabolic Syndrome Author: R. Peterson 5) Mouse Models of Huntingdon's Disease Author: L. Menalled, M. Chesselet 6) Mouse Models for Ocular Disease Author: L. Molday 7) Hyperlipidemia-Induced Atherosclerosis Author: A. Daugherty 8) Mouse Models for Mitochondrial Disease Authors: D. Wallace

「Nielsen BookData」 より

詳細情報

• NII書誌ID(NCID): BA88497734
• ISBN:
  • 9780123744548
• 出版国コード: us
• タイトル言語コード: eng
• 本文言語コード: eng
• 出版地: San Diego, Calif. ; London
• ページ数/冊数: xv, 493 p., [18] p. of plates
• 大きさ: 24 cm
• 分類:
  • DC22 : 616.027333
• 件名:
  • LCSH : Diseases -- Animal models
  • LCSH : Mice as laboratory animals
• 親書誌ID:
  • BA00305828