RNA viruses : host gene responses to infections
著者
書誌事項
RNA viruses : host gene responses to infections
World Scientific, c2009
- : hbk
大学図書館所蔵 全5件
  青森
  岩手
  宮城
  秋田
  山形
  福島
  茨城
  栃木
  群馬
  埼玉
  千葉
  東京
  神奈川
  新潟
  富山
  石川
  福井
  山梨
  長野
  岐阜
  静岡
  愛知
  三重
  滋賀
  京都
  大阪
  兵庫
  奈良
  和歌山
  鳥取
  島根
  岡山
  広島
  山口
  徳島
  香川
  愛媛
  高知
  福岡
  佐賀
  長崎
  熊本
  大分
  宮崎
  鹿児島
  沖縄
  韓国
  中国
  タイ
  イギリス
  ドイツ
  スイス
  フランス
  ベルギー
  オランダ
  スウェーデン
  ノルウェー
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注記
Includes bibliographical references and index
内容説明・目次
内容説明
This is the first comprehensive book on human/animal gene responses to RNA viral infections, including prevalent, emerging and re-emerging RNA viruses such as HIV, SARS-CoV, West Nile virus, influenza virus and many others. Human gene responses are reviewed by leading virologists worldwide in the following aspects: (i) the altered gene expression profiles at the transcriptional and translational levels detected with cutting-edge technologies such as cDNA microarray and proteomics; (ii) host innate and adapted immune responses to viral replication in target organs; (iii) virus-activated signal transduction pathways in cell survival, apoptosis and autophagosomal pathways; and (iv) the small interfering RNA/microRNA-mediated gene silencing pathway, a recently characterized new host defense mechanism against viral infection.Organized into 27 highly accessible and well-illustrated chapters, this volume explores state-of-the-art knowledge of the molecular mechanisms of RNA virus infection and host-virus interactions. This comprehensive compilation of the altered gene expression profiles and signal transduction pathways in host cells in response to the majority of human/animal RNA viruses opens new directions for basic and clinical research on viral pathogenesis, and also provides valuable biomarkers for researchers to select gene targets in the development of diagnostic tests and antiviral therapeutics for a number of infectious diseases.
目次
- Retrovirus: Efforts to Characterize Host Response to HIV-1 Infection (M Montano & P Sebastiani)
- Host Immune Responses in HIV Infection (R D Allison & S Kottilil)
- Negative Single-Stranded RNA Virus: Host Immune Response to Influenza Virus (T M Moran & C B Lopez)
- Innate Recognition of Viral Infection and the Involvement of Autophagy (B Ramanathan & A Iwasaki)
- Hantavirus Infection and Innate Immunity (N Sen et al.)
- Positive Single-Stranded RNA Virus: Impact of Filovirus Infection upon Cellular Signaling Pathways (C F Basler)
- Host Signaling Responses to Coxsackievirus Infection (G Gao et al.)
- Double-Stranded RNA Virus: Host Signaling Responses to Reovirus Infection (D Pan et al.)
- Rotavirus Antagonism of the Host Innate Immune Response (J T Patton & M Barro)
- and other papers.
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