Lectins
著者
書誌事項
Lectins
Springer, c2007
2nd ed
- : pbk
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注記
Bibliography: p. 381-440
Includes index
内容説明・目次
内容説明
This Second Edition brings readers up to date with all the latest findings in lectin research. Throughout this new edition, more than 200 figures and some thirty tables help readers visualize and understand key concepts and processes. The book starts with an overview of lectin research followed by a survey of the occurrence of lectins in nature. Other areas covered include the nutritional effects of lectins and their functions in nature.
目次
- Preface. 1. Introduction. 2. History: The Early Pioneers
- Blood Group Specificity
- Mitogenic Stimulation
- A Tool For Cancer Research
- Lectins Galore
- From Primary To Three-Dimensional Structures
- Tools For Biological And Medical Research
- Insight Into Biological Functions
- Into Contemporary Lectin Research. 3. Detection, Occurrence And Isolation: Detection
- Occurrence
- Isolation And Purification. 4. Specificity And Affinity: Methodology
- Carbohydrate Specificity
- Role Of Oligosaccharide Conformation
- Effect Of Multivalency
- Energetics Of Protein-Carbohydrate Interactions
- Non-Carbohydrate Ligands
- Leczymes. 5. Molecular Structure: Plant Lectins
- Animal Lectins
- Protozoan Lectins
- Bacterial Lectins
- Viral Hemagglutinins. 6. Combining Sites: Lectin-Carbohydrate Bonds
- Plant Lectins
- Animal Lectins
- Bacterial Lectins
- Viral Hemagglutinins. 7. Genetics, Molecular Biology And Evolution: Genetics And Molecular Biology
- Evolution Of Carbohydrate Binding Activity. 8. Applications: Methodology
- Glycoconjugates In Solution
- Cell-Bound Carbohydrates
- Mapping Neuronal Pathways
- Cell Separation
- Mitogenic Stimulation
- Anti-Adhesion Therapy
- Clinical Uses
- Diagnosis And Targeting
- Other Applications. 9. Lectin Cytotoxicity And Lectin-Resistant Cells: Mechanism Of Action
- Lectin-Resistant Mutants. 10. Nutritional Effects: Lectins In Edible Plants
- Deleterious Effects In The Intestinal Tract
- Systemic Effects. 11. Functions: Theoretical Considerations
- Plant Lectins
- Animal Lectins
- Microbial Lectins. Abbreviations. Appendix 1: Monosaccharides Recognized By Lectins. Appendix 2: Disaccharides And Oligosacharides. References. Index.
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