Nanotechnology and tissue engineering : the scaffold

著者

    • Laurencin, Cato T.
    • Nair, Lakshmi S.

書誌事項

Nanotechnology and tissue engineering : the scaffold

Cato T. Laurencin, Lakshmi S. Nair, [editors]

CRC Press, c2008

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注記

Includes bibliographical references and index

内容説明・目次

内容説明

Nanofabrication gives us the ability to mimic biological structures with molecular level precision. Offering a natural progression of topics, Nanotechnology and Tissue Engineering: The Scaffold provides a state-of-the-art account of groundbreaking research in this rapidly emerging area of biomedical engineering. Emphasizing the importance of scaffolds, the book details fundamental and advanced aspects of nanofabrication and examines cellular interactions at the nanoscale level. It reviews extracellular matrix structure and function and discusses various nanoscale biological surface modifications that can improve cellular responses. The editors present the most promising nanofabrication techniques, including electrospinning, lithography, and self assembly. Featuring the contributions of pioneering scientists writing about their own research, this cutting-edge volume - Provides background information discussing the emerging importance of scaffolds in tissue engineering Examines tissue engineering as it relates to orthopedic, cardiovascular, neural, and musculoskeletal applications Details cell responses to a number of nanoscale features Delves into microfabrication techniques in scaffold development Presents research on designer self-assembling peptide scaffolds This highly comprehensive resource also discusses clinical implications and applications, presenting exciting breakthroughs in neural, vascular, and musculoskeletal tissue engineering with nanostructures. An essential resource, for biomedical engineers working on the frontiers of tissue research, this book brings together current findings and background information on a complete range of engineering processes that have led to the development of a number of highly useful tissues.

目次

SECTION I: Importance of Scaffolds in Tissue Engineering Tissue Engineering: The Therapeutic Strategy of the Twenty-First Century, F. Yang, W.L. Neeley, M.J. Moore, J.M. Karp, A. Shukla, and R. Langer Top-Down Analysis of a Dynamic Environment: Extracellular Matrix Structure and Function, M. Veiseh, E.A. Turley, and M.J. Bissell Functions and Requirements of Synthetic Scaffolds in Tissue Engineering, T. Shyam Karande and C. Mauli Agrawal Microfabrication Techniques in Scaffold Development, C.J. Bettinger, J.T. Borenstein, and R. Langer SECTION II: Effect of Nanostructures on Cellular Responses and Tissue Regeneration Cell Response to Nanoscale Features and Its Implications in Tissue Regeneration: An Orthopedic Perspective, B. Ercan and T. Webster Surface Modification of Biomaterials at the Nanoscale: Biomimetic Scaffolds for Tissue Engineering Applications, D.A. Lee and C.T. Laurencin SECTION III: Promising Nanofabrication Techniques to Develop Scaffolds for Tissue Engineering Electrospun Polymeric Nanofiber Scaffolds for Tissue Regeneration, S. Prasad Nukavarapu, S.G. Kumbar, J.G. Merrell, and C.T. Laurencin Structure and Mechanical Properties of Electrospun Nanofibers and Nanocomposites, E. Phay Shing Tan and C. Teck Lim Electrospinning Techniques to Control Deposition and Structural Alignment of Nanofibrous Scaffolds for Cellular Orientation and Cytoskeletal Reorganization, J.K. Wise, M. Cho, E. Zussman, C.M. Megaridis, and A.L. Yarin Nanolithographic Techniques in Tissue Engineering, B. Moody and G.S. McCarty Designer Self-Assembling Peptide Scaffolds for Tissue Engineering and Regenerative Medicine, A. Horii, X. Wang, and S. Zhang SECTION IV: Applications of Nanostructured Scaffolds in Biology and Medicine Nanotechnologies in Neural Tissue Engineering, V. Mukhatyar, J. Yeh, and R. Bellamkonda Nanotechnologies for Cardiovascular Tissue Engineering, K.A. Wieghaus and E.A. Botchwey Nanostructures for Musculoskeletal Tissue Engineering, S. Liao, C.K. Chan, and S. Ramakrishna Index

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