Nuclear receptors as drug targets
Author(s)
Bibliographic Information
Nuclear receptors as drug targets
（Methods and principles in medicinal chemistry / edited by R. Mannhold ... [et al.], v. 39）
Wiley-VCH, c2008
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Note
Includes bibliographical references and index
Description and Table of Contents
Description
Edited by two experts working at the pioneering pharmaceutical company and major global player in hormone-derived drugs, this handbook and reference systematically treats the drug development aspects of all human nuclear receptors, including recently characterized receptors such as PPAR, FXR and LXR. Authors from leading pharmaceutical companies around the world present examples and real-life data from their own work.
Table of Contents
Nuclear Receptors as Modern Drug Targets - a Historic Perspective
Targeting the Nuclear Receptor -
Cofactor Interaction
Untangling the Estrogen Receptor Web
Subtype Selective Estrogens
Estrogen Receptors as Therapeutic Targets in Breast Cancer
Progesterone Receptor and Progestines
Progesterone Receptor Antagonists
Nonsteroidal Tissue Selective Androgen Receptor Modulators
The Glucocorticoid Receptor as Target for Classic and Novel Anti-inflammatory Therapy and Novel Glucocorticoid Receptor Ligands
Vitamin D Analogs as Modulators of Vitamin D Receptor Action
PPARs: Therapeutic Targets for Metabolic Disease and Type 2 Diabetes
Retinoids in Clinical Use
Nuclear Receptors as Targets in Cardiovascular Diseases
NURR77 Family of Nuclear Receptors and its Modulators
Induction of Drug Metabolism: The Role of Nuclear Receptors
Nuclear Receptor Targeted Screening Libraries and Chemogenomics Approaches
by "Nielsen BookData"
