Nuclear receptors as drug targets

著者

• Ottow, Eckhard, 1953
• Weinmann, Hilmar

書誌事項

Nuclear receptors as drug targets

edited by Eckhard Ottow and Hilmar Weinmann

（Methods and principles in medicinal chemistry / edited by R. Mannhold ... [et al.], v. 39）

Wiley-VCH, c2008

注記

Includes bibliographical references and index

内容説明・目次

内容説明

Edited by two experts working at the pioneering pharmaceutical company and major global player in hormone-derived drugs, this handbook and reference systematically treats the drug development aspects of all human nuclear receptors, including recently characterized receptors such as PPAR, FXR and LXR. Authors from leading pharmaceutical companies around the world present examples and real-life data from their own work.

目次

Nuclear Receptors as Modern Drug Targets - a Historic Perspective Targeting the Nuclear Receptor - Cofactor Interaction Untangling the Estrogen Receptor Web Subtype Selective Estrogens Estrogen Receptors as Therapeutic Targets in Breast Cancer Progesterone Receptor and Progestines Progesterone Receptor Antagonists Nonsteroidal Tissue Selective Androgen Receptor Modulators The Glucocorticoid Receptor as Target for Classic and Novel Anti-inflammatory Therapy and Novel Glucocorticoid Receptor Ligands Vitamin D Analogs as Modulators of Vitamin D Receptor Action PPARs: Therapeutic Targets for Metabolic Disease and Type 2 Diabetes Retinoids in Clinical Use Nuclear Receptors as Targets in Cardiovascular Diseases NURR77 Family of Nuclear Receptors and its Modulators Induction of Drug Metabolism: The Role of Nuclear Receptors Nuclear Receptor Targeted Screening Libraries and Chemogenomics Approaches

「Nielsen BookData」 より

• NII書誌ID(NCID): BA89198728
• ISBN:
  • 9783527318728
• 出版国コード: gw
• タイトル言語コード: eng
• 本文言語コード: eng
• 出版地: Weinheim
• ページ数/冊数: xxiv, 498 p
• 大きさ: 25cm
• 分類:
  • DC22 : 615.7
• 件名:
  • LCSH : Drug receptors
  • LCSH : Nuclear receptors (Biochemistry)
  • LCSH : Drug targeting
• 親書誌ID:
  • BA22871556