Dynamics of the mammalian sperm head : modifications and maturation events from spermatogenesis to egg activation
Author(s)
Bibliographic Information
Dynamics of the mammalian sperm head : modifications and maturation events from spermatogenesis to egg activation
（Advances in anatomy, embryology and cell biology, 204）
Springer, c2009
Available at 3 libraries
Note
"With 36 Figures"
Includes bibliographical references (p. [81]-94) and index
Description and Table of Contents
Description
Mammalian spermatozoa have complex structures. The structure-function relationship of sperm has been studied from various viewpoints. Accumulated evidence has shown that the sperm components undergo sequential changes from the beginning of spermatogenesis to the time of fertilization/embryogenesis. Structural analyses have been performed using various new techniques of light and electron microscopy as well as immunohistochemistry and immunocytochemistry in combination with specific probes such as antibodies against sperm components. Recently developed gene-manipulation techniques have accelerated investigations on the events that govern the relationship between the structure and molecular components of sperm. In addition, animal models with gene manipulations have been shown to exhibit various morphological and functional abnormalities that lead to infertility.
In this book, I discuss the events that occur in the normal sperm head and govern the structure-function relationship from the time of spermatogenesis to that of fertilization or egg activation. In this regard, I describe dynamic modifications and maturation events occurring in sperm-head components and compare the outcomes of these events with the outcomes of their failure.
Table of Contents
1 Introduction.- 2 Mammalian sperm head.- 3 Sperm head formation and factors affecting it.- 4 Post-testicular modifications and maturation events occurring in the sperm head.- 5 Dynamics of the acrosome.- 6 Dynamics of the perinuclear theca.- 7. Dynamics of the sperm nucleus.- 8. Dynamics of the membrane system.- 10 Status of sperm-head components during normal fertilization, IVF, ICSI, and round spermatid injection.- 11 Conclusion.- References.- Subject index.
by "Nielsen BookData"