Biomaterials and tissue engineering in urology

著者

書誌事項

Biomaterials and tissue engineering in urology

edited by John Denstedt and Anthony Atala

（Woodhead publishing in materials）

Woodhead , CRC Press, 2009

  • : Woodhead
  • : CRC

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注記

Includes bibliographical references and index

内容説明・目次

巻冊次

: CRC ISBN 9781439801772

内容説明

An invaluable resource for clinicians as well as for researchers in materials and biomedical devices, this text summarizes recent research on the use of biomaterials and tissue engineering in the treatment of urological disorders. Part one reviews the fundamentals including biofilms and encrustation formation. Part two then discusses recent advances in biomaterials and the design of urological devices such as metal ureteral stents, self-lubricating catheter materials, and penile implants. The final section addresses urological tissue engineering, covering artificial and natural biomaterials, nanotechnology, and placental stem cells used for the regeneration of urological tissue and organs.

目次

  • PART 1 FUNDAMENTALS Introduction to biofilms in urology, P Cadieux, G Wignall and R Carriveau, University of Western Ontario, Canada Introduction. What is a biofilm and why do they form? Biofilm formation and structure. Biofilms in general medicine. Biofilms in urology. Biofilm shedding and migration: infection spread and recurrence. Resistance to host factors and antibiotics. Current and future biofilm prevention and treatment strategies. Future trends. Conclusions. Sources of further information and advice. References. In vivo models for ureteral stents, M K Louie, A J Gamboa and R V Clayman, UCI Medical Center, USA Introduction. Commonly used animal models for ureteral stents. Conclusions and future trends. References. Models for the assessment of biofilm and encrustation formation on urological materials, B F Gilmore, D S Jones and S P Gorman, Queen's University Belfast, Northern Ireland
  • and H Ceri, University of Calgary, Canada Introduction. Development of urinary encrustation. Assessment of biomaterial encrustation: in vitro models. Dynamic flow-through models. Batch-flow or `static' models. Dynamic continuous flow models. The MBEC-BEST (TM) assay. Conclusions. References. PART 2 MATERIALS AND DESIGN OF UROLOGICAL DEVICES Ureteral stents: design and materials, D Lange and B H Chew, University of British Columbia, Canada Introduction. Current stent biomaterials. Stent coatings. Stent design. Drug eluting stents. Conclusions and future trends. References. Metal stents in the upper urinary tract, E Liatsikos, D Karnabatidis, P Kallidonis and D Siablis, University of Patras, Greece Introduction. Types of metal stents in the upper urinary tract. Applications of metal stents. Insertion techniques. Complications and problems. Virtual endoscopy and metal stents. Extra-urinary drainage of the upper urinary tract. Future trends. References. Coated ureteral stents, F Cauda, Ospedale Koelliker, Italy, V Cauda, Ludwig Maximilians Universitat Munchen, Germany and C Fiori, Azienda Ospedaliero-Universitaria San Luigi Gonzaga, Italy Introduction. Methods. Results. Discussion. Conclusions. Acknowledgement. References. Biofilm formation and catheter design, D J Stickler, Cardiff University, UK Introduction. Virulence factors. Epidemiology of P. mirabilis infections. The process of crystalline biofilm formation on catheters. Antimicrobials in the prevention of catheter encrustation. Factors that modulate the rate of P. mirabilis biofilm formation on catheters. Urease inhibitors. Catheter design. Future trends. Conclusions. Sources of further information and advice. References. Self-lubricating catheter materials, A D Woolfson, R K Malcolm, S P Gorman and S D McCullagh, Queen's University Belfast, UK Introduction. Silicone chemistry. Self-lubricating silicone biomaterials. Performance characteristics of self-lubricating silicone biomaterials. Bioactive lubricious silicones. Biomimetic lubricious silicones. Toxicity and regulatory issues. Conclusions. References. Temporary urethral stents, T Tammela, Tampere University Hospital, Finland Introduction. Indications to use stents. Nondegradable temporary urethral stents. Biodegradable urethral stents. Future trends. References. Penile implants, G Brock, University of Western Ontario, Canada Introduction. Historical aspects of penile prosthesis development. Biomaterials in current use. Device infection. Erosion resistance. Summary. Future trends. References. PART 3 UROLOGICAL TISSUE ENGINEERING Artificial biomaterials for urological tissue engineering, W A Farhat, The Hospital for Sick Children, Canada and P J Geutjes, Radboud University Nijmegen Medical Centre, The Netherlands Introduction. History of artificial based biomaterials used in urology. Synthetic scaffolds. Smart biomaterials. References. Natural biomaterials for urological tissue engineering, C C Roth and B P Kropp, The University of Oklahoma Health Sciences Center and E Y Cheng, Children's Memorial Hospital in Chicago, USA Introduction. Historical applications of natural biomaterials. Fundamental biomaterials. Collagen based extracellular matrices. Future trends. Sources of further information and advice. References. Nanotechnology and urological tissue engineering, B S Harrison and C Ward, Wake Forest Institute for Regenerative Medicine, USA Introduction. Rationale for nanomaterials in engineering tissue. Use of nanomaterials as biomaterials. Use of nanomaterials for aiding cell tracking. Use of nanomaterials to improve drug delivery. Conclusions. Future trends. Sources of further information and advice. References. Assessing the performance of tissue-engineered urological implants, G J Christ, D Burmeister, S Vishwajit, Y Jarajapu and K-E Andersson, Wake Forest Institute for Regenerative Medicine, USA Introduction. The bladder. Evaluation of engineered or regenerating tissues in vitro. Bladder tissue engineering and regeneration. Conclusions and future trends. References. Regenerative pharmacology and bladder regeneration, K-E Andersson and G J Christ, Wake Forest Institute for Regenerative Medicine, USA Introduction. Endogenous bladder regeneration. Construction of a tissue or organ. Development of an engineered bladder. Implantation of the bladder construct in preclinical studies. Preliminary clinical experience with neobladders. Conclusions. Acknowledgments. References. Autologous cell sources for urological applications, Y Zhang, Wake Forest Institute for Regenerative Medicine, USA Introduction. Fully-differentiated cells for urological reconstruction. Stem and progenitor cells for urological reconstruction. Cell tracking technology. Conclusions. Acknowledgements. References. Embryonic stem cells, nuclear transfer, and parthenogenesis-derived stem cells for urological reconstruction, R Dorin, J Yamzon, and C J Koh, Children's Hospital Los Angeles and USC Keck School of Medicine, USA Introduction. Principles of tissue engineering. Stem cells overview. Embryonic stem cells. Nuclear transfer. Parthenogenesis. Induced pluripotent stem cells. Conclusions and future trends. References. Amniotic fluid and placental stem cells as a source for urological regenerative medicine, P De Coppi, UCL Institute of Child Health and Great Ormond Street Hospital, UK, Azienda Ospedaliera Universita di Padova, Italy, G Bartsch, University of Ulm, Germany and A Atala, Wake Forest Institute for Regenerative Medicine, USA Introduction. Amniocentesis. Differentiated cells from amniotic fluid. Mesenchymal stem cells from amniotic fluid. Amniotic fluid-derived stem cells. Conclusions. References. The use of adipose progenitor cells in urology, D S Dave and L V Rodriguez, University of California Los Angeles, USA Introduction. Nomenclature and origin of adipose progenitor cells. Isolation procedures. Molecular characterization. Differentiation capacity of adipose-derived stem cells. Applications in the field of urology. Future trends. References. Regenerative medicine of the urinary sphincter via an endoscopic approach, M C Smaldone, University of Pittsburgh School of Medicine and M B Chancellor, William Beaumont Hospital, USA Overview. Introduction. Neurophysiology of stress urinary incontinence. Stem cell source for the injection therapy of stress urinary incontinence (SUI). Role of muscle-derived stem cells (MDSCs) in the delivery of neurotrophic factors. Injection technique. Current results of clinical studies. Conclusions. References. Regenerative medicine of the urinary sphincter via direct injection, R Yiou, CHU Henri Mondor, France Introduction. Challenges with muscle precursor cells (MPC) transfer. The direct myofiber implantation procedure. Direct injection of muscle precursor cells using minced muscle. Conclusions and future trends. References. Regenerative medicine for the urethra, T Aboushwareb and A Atala, Wake Forest Institute for Regenerative Medicine, USA and A ElKassaby, Shams University, Egypt Introduction. Synthetic scaffolds. Biologic (natural) polymers. Acellular dermal matrix. Cadaveric fascia lata. Amniotic membrane. Small intestinal submucosa. Bladder acellular matrix graft. Conclusions. Acknowledgement. References. Penile reconstruction, H-J Wang and J J Yoo, Wake Forest Institute for Regenerative Medicine, USA Introduction. Basic principles of penile tissue engineering. Engineering of functional corporal tissue. Engineered penile prosthesis. Reconstruction of the tunica albuginea. Summary and future trends. Acknowledgment. References. Tissue engineering in reproductive medicine, A Sophonsritsuk and C E Bishop, Wake Forest Institute for Regenerative Medicine, USA Tissue engineering of the vagina. Methods of vaginal tissue reconstitution. Tissue engineering of the uterus. Methods of uterine tissue reconstitution. Tissue engineering of the ovarian tissue. Method for culturing follicles. Conclusions. Acknowledgement. References. Regenerative medicine of the kidney, N Guimaraes-Souza, R Soler and J J Yoo, Wake Forest Institute for Regenerative Medicine, USA Introduction. Basic components of renal tissue engineering. Approaches for the regeneration of renal tissue. Cell based therapy for kidney disease. Summary. Acknowledgement. References. Stem cells and kidney regeneration, S Sedrakyan, L Perin and R E De Filippo, University of Southern California, USA Introduction. Endogenous stem cells. Exogenous stem cells. Conclusions. References.
巻冊次

: Woodhead ISBN 9781845694029

内容説明

Urology is the branch of medicine dealing with disorders or diseases of the male genitor-urinary tract and the female urinary tract. This important book summarises the wealth of recent research on the use of biomaterials and tissue engineering to treat urological disorders. Part one reviews the fundamentals with chapters on such topics as biofilms and encrustation formation. Part two then discusses recent advances in biomaterials and design of urological devices such as metal ureteral stents, self-lubricating catheter materials and penile implants. Chapters in Part three address urological tissue engineering with coverage of themes such as artificial and natural biomaterials, nano-technology and placental stem cells for tissue engineering the regeneration of urological tissue and organs. With its eminent editors and international team of contributors, Biomaterials and tissue engineering in urology is an invaluable resource to researchers of urological biomaterials, devices and regenerative medicine in both industry and academia, as well as an important reference for medical practitioners.

目次

  • Part 1 Fundamentals: Introduction to biofilms in urology: In vivo models for ureteral stents
  • Models for the assessment of biofilm and encrustation formation on urological materials. Part 2 Materials and design of urological devices: Ureteral stents: Design and materials
  • Metal stents in the upper urinary tract
  • Coated ureteral stents
  • Proteus mirabilis biofilm formation and catheter design
  • Self-lubricating catheter materials
  • Temporary urethral stents
  • Penile implants. Part 3 Urological tissue engineering: Artificial biomaterials for urological tissue engineering
  • Natural biomaterials for urological tissue engineering
  • Nanotechnology and urological tissue engineering
  • Assessing the performance of tissue-engineered urological implants
  • Regenerative pharmacology and bladder regeneration
  • Autologous cell sources for urological applications
  • Embryonic stem cells, nuclear transfer, and parthenogenesis-derived stem cells for urological reconstruction
  • Amniotic fluid and placental stem cells as a source for urological regenerative medicine
  • The use of adipose progenitor cells in urology
  • Regenerative medicine of the urinary sphincter via an endoscopic approach
  • Regenerative medicine of the urinary sphincter via direct injection
  • Regenerative medicine for the urethra
  • Penile reconstruction
  • Tissue engineering in reproductive medicine
  • Regenerative medicine of the kidney
  • Stem cells and kidney regeneration
  • Techniques for engineering bladder tissue.

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