Imaging the aging brain

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Bibliographic Information

Imaging the aging brain

edited by William Jagust, Mark D'Esposito

Oxford University Press, 2009

Available at  / 7 libraries

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Note

Includes bibliographical references and index

Contents of Works

  • Methodological and conceptual issues in the study of the aging brain / Mark D'Esposito, William Jagust, and Adam H. Gazzaley
  • Neuropathology of aging / Dara L. Dickstein, John H. Morrison, and Patrick R. Hof
  • A systems approach to the aging brain : neuroanatomic changes, their modifiers, and cognitive correlates / Naftali Raz and Kristen M. Kennedy
  • Dopaminergic modulation of cognition in human aging / Shu-Chen Li ... [et al.]
  • Cognitive reserve and aging / Yaakov Stern
  • Compensatory reorganization of brain networks in older adults / Cheryl L. Grady
  • Cross-species imaging applied to the aging brain : dissociating Alzheimer's disease from normal aging / Sidonie T. Jones and Scott A. Small
  • Genetics and imaging in Alzheimer's disease / Susan Y. Bookheimer
  • Imaging cognitive decline in aging : predicting decline with structural imaging / Jeffrey Kaye
  • The early detection of Alzheimer's disease with positron emission tomography / Rachel Mistur ... [et al.]
  • Structural imaging of mild cognitive impairment / Clifford R. Jack, Jr.
  • Functional imaging with FDG-PET in mild cognitive impairment / Karl Herholz
  • Amyloid imaging and (what is "normal") aging / William E. Klunk and Chester A. Mathis
  • Differential diagnosis of dementia using functional neuroimaging / Eric Salmon, Fabienne Collette, and Gaëtan Garraux
  • MRI and the differential diagnosis of dementia / António J. Bastos-Leite and Philip Scheltens
  • White matter hyperintensities in aging and dementia / Adriane Mayda, Mitsuhiro Yoshita, and Charles DeCarli
  • Functional MRI studies in aging and early Alzheimer's disease : predicting clinical decline / Reisa Sperling
  • MRI as a surrogate marker in clinical trials in Alzheimer's disease / Frank Jessen and Harald Hampel
  • Brain imaging in the evaluation of putative Alzheimer's disease slowing, risk-reducing, and prevention therapies / Eric M. Reiman and Jessica B.S. Langbaum
  • Databasing the aging brain / John Darrell Van Horn and Arthur W. Toga

Description and Table of Contents

Description

This book contains chapters from experts in the fields of brain imaging, clinical neuroscience, and cognitive neuroscience who have studied the aging brain. Topics covered include technical factors in brain imaging, pathological basis of age-related structural and functional changes, neurochemistry and genetics of brain imaging in aging, and the use of imaging techniques in diagnosis, longitudinal testing, drug development and testing, and presymptomatic detection. The book is intended to be both a detailed review of the current status of brain imaging and aging and to serve as an introduction to the field for those who may be starting investigations using imaging techniques of PET, structural MRI, and functional MRI. It covers basic science approaches such as using fMRI to probe networks, as well as recent developments like amyloid imaging and the use of imaging as a biomarker in clinical trials.

Table of Contents

1. Introduction: Still More Questions than Answers William Jagust and Mark D'Esposito 2. Methodological and Conceptual Issues in the Study of the Aging Brain Mark D'Esposito, William Jagust and Adam H. Gazzaley 3. Neuropathology of Aging Dara L. Dickstein, John H. Morrison and Patrick R. Hof Basic Science 4. A Systems Approach to Age-Related Change: Neuroanatomic Changes, Their Modifiers, and Cognitive Correlates Naftali Raz and Kristen M. Kennedy 5. Dopaminergic Modulation of Cognition in Human Aging Shu-Chen Li, Ulman Lindenberger, Lars Nyberg, Hauke R. Heekeren, and Lars Backman 6. Cognitive Reserve Yaakov Stern 7. Compensatory Reorganization of Brain Networks in Older Adults Cheryl L. Grady 8. Cross-species Imaging Applied to the Aging Brain: Dissociating Alzheimer's Disease From Normal Aging Scott A. Small and Sidonie Jones 9. Genetics and Imaging in Alzheimer's Disease Susan Y. Bookheimer Clinical Applications 10. Imaging Cognitive Decline in Aging: Predicting Decline with Structural Imaging Jeffrey Kaye 11. The Early Detection of Alzheimer's Disease with Positron Emission Tomography Rachel Mistur, Lisa Mosconi, Remigiusz Switalski, Susan De Santi, Yi Li, Lisa Glodzik-Sobanska, Miroslaw Brys, Wai Tsui, Henry Rusinek, Mony de Leon 12. Structural Imaging of Mild Cognitive Impairment Clifford R. Jack, Jr. 13. Functional Imaging with FDG-PET in Mild Cognitive Impairment Karl Herholz 14. Amyloid Imaging and (What is "Normal") Aging William E. Klunk and Chester A. Mathis 15. Differential Diagnosis of Dementia using Functional Neuroimaging Eric Salmon, Fabienne Collette, and Gaetan Garraux 16. MRI and the Differential Diagnosis of Dementia Antonio J. Bastos-Leite and Philip Scheltens 17. White Matter Hyperintensities in Aging and Dementia Adriane Mayda, Mitsuhiro Yoshita, and Charles DeCarli 18. Functional MRI Studies in Aging and Early Alzheimer's Disease: Predicting Clinical Decline Reisa Sperling and Harald Hampel 19. MRI as a Surrogate Marker in Clinical Trials in Alzheimer's Disease Frank Jessen and Harald Hampel 20. Brain Imaging in the Evaluation of Putative Alzheimer's Disease Slowing, Risk-Reducing, and Prevention Therapies Eric M. Reiman and Jessica B.S. Langbaum 21. Databasing the Aging Brain John Darrell Van Horn and Arthur W. Toga

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