Small molecules in oncology
著者
書誌事項
Small molecules in oncology
（Recent results in cancer research, 184）
Springer, c2010
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注記
Includes bibliographical references
内容説明・目次
内容説明
Written by acknowledged experts, this text provides a broad overview of the small molecules currently used for the treatment of malignant diseases, and discusses interesting novel compounds that are in the process of clinical development to combat cancer.
目次
Protein kinase inhibitors.- Imatinib Mesylate.- Erlotinib.- Axitinib (AG-013736).- Lapatinib.- Sorafenib.- Sunitinib.- Dasatinib.- Nilotinib.- Bosutinib.- Epigenetic modifiers.- Decitabine.- 5-Azacytidine/Azacitidine.- Cell cycle inhibitors.- Bortezomib.- Temsirolimus.- Danusertib (formerly PHA-739358) - A Novel Combined Pan-Aurora Kinases and Third Generation Bcr-Abl Tyrosine Kinase Inhibitor.- BI_2536 - Targeting the Mitotic Kinase Polo-Like Kinase 1 (Plk1).- Other novel agents.- Imetelstat (GRN163L) - Telomerase-Based Cancer Therapy.- GDC-0449 - Targeting the Hedgehog Signaling Pathway.
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