Antimicrobial drug resistance

Author(s)

    • Mayers, Douglas L.
    • Lerner, Stephen A.
    • Ouellette, Marc
    • Sobel, Jack D.

Bibliographic Information

Antimicrobial drug resistance

edited by Douglas L.Mayers ; section editors, Stephen A.Lerner, Marc Ouellette, Jack D.Sobel

(Infectious disease)

Humana Press, c2009

  • v. 1
  • v. 2

Available at  / 2 libraries

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Note

Formerly CIP Uk

Includes bibliographical references and index

v. 1. Mechanisms of drug resistance

v. 2. Clinical and epidemiological aspects

Description and Table of Contents

Volume

v. 1 ISBN 9781603275927

Description

This ? rst edition of Antimicrobial Drug Resistance grew out of a desire by the editors and authors to have a comprehensive resource of information on antimicrobial drug resistance that encompassed the current information available for bacteria, fungi, protozoa and viruses. We believe that this information will be of value to clinicians, epidemiologists, microbiologists, virologists, parasitologists, public health authorities, medical students and fellows in training. We have endeavored to provide this information in a style which would be accessible to the broad community of persons who are concerned with the impact of drug resistance in our cl- ics and across the broader global communities. Antimicrobial Drug Resistance is divided into Volume 1 which has sections covering a general overview of drug resistance and mechanisms of drug resistance ? rst for classes of drugs and then by individual microbial agents including bacteria, fungi, protozoa and viruses. Volume 2 addresses clinical, epidemiologic and public health aspects of drug resistance along with an overview of the conduct and interpretation of speci? c drug resistance assays. Together, these two volumes offer a comprehensive source of information on drug resistance issues by the experts in each topic.

Table of Contents

General Overview.- History of Drug-Resistant Microbes.- Evolutionary Biology of Drug Resistance.- Pharmacology of Drug Resistance.- Antimicrobial Resistance Versus the Discovery and Development of New Antimicrobials.- General Mechanisms of Drug Resistance.- Genetic Mechanisms of Transfer of Drug Resistance.- Mutations as a Basis of Antimicrobial Resistance.- Target-Mediated Antibacterial Resistance.- Biochemical Logic of Antibiotic Inactivation and Modification.- Antibiotic Resistance Due to Reduced Uptake.- Transport Mechanisms of Resistance to Drugs and Toxic Metals.- The Functional Resistance of Bacterial Biofilms.- Bacterial Drug Resistance - Mechanisms.- The Importance of ?-Lactamases to the Development of New ?-Lactams.- Penicillin-Binding Proteins and ?-Lactam Resistance.- Aminoglycosides: Mechanisms of Action and Resistance.- Tetracycline and Chloramphenicol Resistance Mechanisms.- Fluoroquinolone Resistance in Bacteria.- Plasmid-Mediated Quinolone Resistance.- Macrolides and Lincosamides.- Mechanism of Resistance in Metronidazole.- Glycopeptide Resistance in Enterococci.- Streptogramin.- Resistance to Linezolid.- Sulfonamides and Trimethoprim.- Mechanisms of Action and Resistance of Antimycobacterial Agents.- Fungal Drug Resistance - Mechanisms.- Amphotericin B: Polyene Resistance Mechanisms.- Fungal Drug Resistance: Azoles.- Flucytosine: Site of Action, Mechanism of Resistance and Use in Combination Therapy.- Echinocandins: Exploring Susceptibility and Resistance.- Antifungal Targets, Mechanisms of Action, and Resistance in Candida albicans.- Viral Drug Resistance - Mechanisms.- Mechanisms of Resistance of Antiviral Drugs Active Against the Human Herpes Viruses.- Influenza M2 Ion-Channel and Neuraminidase Inhibitors.- Molecular Mechanisms of Resistance to Nucleoside Reverse Transcriptase Inhibitors.- Resistance to HIV Non-Nucleoside Reverse Transcriptase Inhibitors.- Resistance to HIV-1 Protease Inhibitors.- Resistance to Enfuvirtide and Other HIV Entry Inhibitors.- Resistance to Inhibitors of Human Immunodeficiency Virus Type I Integration.- The Hepatitis B Virus and Antiviral Drug Resistance: Causes, Patterns, and Mechanisms.- Mechanisms of Hepatitis C Virus Drug Resistance.- Parasitic Drug Resistance - Mechanisms.- Drug Resistance Mechanisms in Entamoeba histolytica, Giardia lamblia, Trichomonas vaginalis, and Opportunistic Anaerobic Protozoa.- Mechanisms of Antimalarial Drug Resistance.- Drug Resistance in Leishmania.- Drug Resistance in African Trypanosomiasis.- Drug Resistance and Emerging Targets in the Opportunistic Pathogens Toxoplasma gondii and Cryptosporidium parvum.- Drug Resistance in Nematodes.- Chemotherapy and Drug Resistance in Schistosomiasis,Fascioliasis and Tapeworm Infections.- Drug Resistance in Ectoparasites of Medical and Veterinary Importance.
Volume

v. 2 ISBN 9781603275941

Description

This ? rst edition of Antimicrobial Drug Resistance grew out of a desire by the editors and authors to have a comprehensive resource of information on antimicrobial drug resistance that encompassed the current information available for bacteria, fungi, protozoa and viruses. We believe that this information will be of value to clinicians, epidemiologists, microbiologists, virologists, parasitologists, public health authorities, medical students and fellows in training. We have endeavored to provide this information in a style which would be accessible to the broad community of persons who are concerned with the impact of drug resistance in our cl- ics and across the broader global communities. Antimicrobial Drug Resistance is divided into Volume 1 which has sections covering a general overview of drug resistance and mechanisms of drug resistance ? rst for classes of drugs and then by individual microbial agents including bacteria, fungi, protozoa and viruses. Volume 2 addresses clinical, epidemiologic and public health aspects of drug resistance along with an overview of the conduct and interpretation of speci? c drug resistance assays. Together, these two volumes offer a comprehensive source of information on drug resistance issues by the experts in each topic.

Table of Contents

Gram-Positive Bacterial Drug Resistance - Clinical.- Resistance in Streptococcus pneumoniae.- Antibiotic Resistance of Non-Pneumococcal Streptococci and Its Clinical Impact.- Enterococcus: Antimicrobial Resistance in Enterococci Epidemiology, Treatment, and Control.- Antimicrobial Resistance in Staphylococci: Mechanisms of Resistance and Clinical Implications.- Resistance in Aerobic Gram-Positive Bacilli.- Gram-Negative Bacterial Drug Resistance - Clinical.- Antibiotic Resistance in Neisseria.- Mechanisms of Resistance in Haemophilus influenzae and Moraxella catarrhalis.- Enterobacteriaceae.- Pseudomonas aeruginosa.- Acinetobacter.- Antimicrobial Resistance of Shigella spp., Typhoid Salmonella and Nontyphoid Salmonella.- Antimicrobial Resistance in Vibrios.- Antimicrobial Resistance in Helicobacter and Campylobacter.- Pertussis (Whooping Cough).- Antibiotic Resistance of Anaerobic Bacteria.- Mycobacteria: Tuberculosis.- Drug Resistance by Non-Tuberculous Mycobacteria.- Fungal Drug Resistance - Clinical.- The Role of Resistance in Candida Infections: Epidemiology and Treatment.- Antifungal Resistance: Aspergillus.- Drug Resistance in Cryptococcus neoformans.- Antifungal Drug Resistance in Histoplasmosis.- Drug Resistance in Pneumocystis jirovecii.- Viral Drug Resistance - Clinical.- Antiviral Resistance in Influenza Viruses: Clinical and Epidemiological Aspects.- Herpesvirus Resistance.- Clinical Implications of HIV-1 Drug Resistance.- Clinical Implications of Resistance for Patients with Chronic Hepatitis B.- Parasitic Drug Resistance - Clinical.- Antimalarial Drug Resistance: Clinical Perspectives.- Diagnosis and Treatment of Metronidazole-Resistant Trichomonas vaginalis Infection.- Drug Resistance in Leishmania: Clinical Perspectives.- Human African Trypanosomiasis.- Drug Resistance in Toxoplasma gondii.- Drug Resistance in the Sheep Nematode Parasite Haemonchus contortus, Mechanisms and Clinical Perspectives.- Measurements of Drug Resistance.- In Vitro Performance and Analysis of Combination Anti-infective Evaluations.- Antimicrobial Susceptibility Testing Methods for Bacterial Pathogens.- Drug Resistance Assays for Mycobacterium tuberculosis.- Fungal Drug Resistance Assays.- Viral Phenotypic Resistance Assays.- Drug Resistance Assays for Parasites.- Genotypic Drug Resistance Assays.- The Use of Genotypic Assays for Monitoring the Development of Resistance to Antiviral Therapy for HIV-1 Infection and Other Chronic Viral Diseases.- Public Health Issues of Drug Resistance.- Antimicrobial Resistance: An International Public Health Problem.- Hospital Infection Control: Considerations for the Management and Control of Drug-Resistant Organisms.- Controlling the Spread of Resistant Pathogens in the Intensive Care Unit.- Implications of Antibiotic Resistance in Potential Agents of Bioterrorism.- Internet Resources on Antimicrobial Resistance.

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