Bone and osteoarthritis

Author(s)

Bibliographic Information

Bone and osteoarthritis

Felix Bronner and Mary C. Farach-Carson (eds.)

(Topics in bone biology, v. 4)

Springer-Verlag, c2007

  • hbk
  • hbk

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Note

Includes bibliographical references and index

Description and Table of Contents

Description

The molecular and cellular approaches to the relationship of joint and bone problems distinguish this from other books on the topic. Advances in bone and joint biology enable practitioners to approach clinical problems more comprehensively. Emphasis on genetics and on newer viewpoints and approaches, exemplified by the possible effect of subchondral bone on osteoarthritis, gives a wider viewpoint to the reader and may enable novel approaches to solving a clinical problem.

Table of Contents

The Pathogenesis of Osteoarthritis.- The Role of Bone in the Development of Osteoarthritis.- Cytokines, Growth Factors, and Bone-Derived Factors in Cartilage.- The Synovium and Its Role in Osteoarthritis.- Cartilage Matrix Destruction.- Anabolic Mediators of Cartilage Healing.- Chondrocyte Hypertrophy and Apoptosis at the Cartilage-Bone Interface.- Genetic and Epigenetic Aspects of Osteoarthritis.- Animal Models.- Biomechanical Aspects: Joint Injury and Osteoarthritis.- Novel Osteoarthritis Therapeutics.

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