The polyamines : small molecules in the 'omics' era
著者
書誌事項
The polyamines : small molecules in the 'omics' era
(Essays in biochemistry, v. 46)
Portland Press, c2009
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注記
Includes bibliographical references and index
Series editor: Melanie Welham (U.K.)
内容説明・目次
内容説明
Metabolism is altered significantly in diseases such as cancer, resulting in the pathway being identified as a target for the design of anticancer drugs. A recent upsurge in interest in the polyamines, including the development of transgenic models, has highlighted the biochemical importance of these molecules.
目次
- The polyamines: past, present and future
- Polyamine homoeostasis
- S-Adenosylmethionine decarboxylase
- Regulation of cellular polyamine levels and cellular proliferation by antizyme and antizyme inhibitor
- Cells and polyamines do it cyclically
- Design of polyamine-based therapeutic agents: new targets and new directions
- Polyamine analogues targeting epigenetic gene regulation
- Polyamines as mediators of APC-dependent intestinal carcinogenesis and cancer chemoprevention
- Transgenic animals modelling polyamine metabolism-related diseases
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