Alcohol, tobacco and cancer

著者

書誌事項

Alcohol, tobacco and cancer

editors, Chi Hin Cho, Vishnudutt Purohit

Karger, c2006

  • : hard cover

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注記

Includes bibliographical references and indexes

HTTP:URL=http://www.loc.gov/catdir/toc/ecip0613/2006013729.html Information=Table of contents

内容説明・目次

内容説明

Excessive alcohol consumption and smoking are among the major risk factors for cancer. Simultaneous indulgence further increases the risk for especially cancer of the upper aerodigestive tract due to the interaction of several metabolic and genetic factors. The first part of this book addresses in detail the correlations between alcohol and carcinogenicity, focusing on specific organs such as the upper aerodigestive tract, liver, colon, pancreas and breast. This includes the impairment of methionine-folate metabolism and DNA methylation by alcohol, as well as the use of s-adenosylmethionine to prevent cancer. Furthermore, the synergistic effects of reactive oxygen species and iron in producing liver cancer are addressed. The second part is dedicated to the role of tobacco in lung and digestive tract cancers and to their prevention, highlighting the role of phytochemicals. More specifically, the mutagenic, mitogenic, precarcinogenic, anti-apoptotic, and immunosuppressive properties of nicotine which are involved in the development of cancer, and the possible use of nicotine vaccine in the prevention of mortality associated with tobacco, are discussed. Highlighting general mechanisms leading to cancer and providing the latest information on the underlying mechanisms whereby alcohol consumption and tobacco use initiate and/or promote carcinogenesis, this book is a valuable source of information for all those interested in the topic.

目次

  • General Cancer
  • General Mechanisms of Cancer: Chan, A.O.O.
  • Wong, B.C.Y.
  • Alcohol and Cancer
  • Epidemiology of Alcohol-Associated Cancers: Brown, L.M.
  • Alcohol Metabolism, Tobacco and Cancer: Zakhari, S.
  • Interaction of Alcohol and Tobacco in Upper Aerodigestive Tract and Stomach Cancer: Salaspuro, M.
  • Salaspuro, V.
  • Seitz, H.K.
  • Alcohol and Cancer of the Large Intestine: Seitz, H.K.
  • Poschl, G.
  • Salaspuro, M.
  • Acetaldehyde-DNA Adducts: Implications for the Molecular Mechanism of Alcohol-Related Carcinogenesis: Brooks, P.J.
  • Theruvathu, J.A.
  • Ethanol and Liver Cancer: McKillop, I.H.
  • Schrum, L.W.
  • Alcohol, Reactive Oxygen Species, Pancreatitis and Pancreatic Cancer: Pandol, S.J.
  • Edderkaoui, M.
  • Lee, J.K.
  • Hu, R.
  • Lugea, A.
  • Sul, J.
  • Apte, M.
  • Vaquero, E.
  • Ohno, I.
  • Gukovsky, I.
  • Go, V.L.W.
  • Gukovskaya, A.S.
  • Alcohol and Breast Cancer Risk: Dumitrescu, R.G.
  • Shields, P.G.
  • Alcohol and Tobacco Smoke in Retinoid Metabolism and Signaling: Implications for Carcinogenesis: Mernitz, H.
  • Wang, X.-D.
  • Role of S-Adenosyl-L-Methionine in Alcohol-Associated Liver Cancer: Lu, S.C.
  • Mato, J.M.
  • Alcohol and Iron as Cofactors in Hepatocellular Carcinoma: Petersen, D.R.
  • Tobacco and Cancer
  • Tobacco Use and Cancer: An Epidemiologic Perspective: Thun, M.J.
  • Tobacco Associated Lung Cancer: Schuller, H.M.
  • Tobacco and Cancer in the Digestive Tract: Waldum, H.L.
  • Martinsen, T.C.
  • Modification of Experimental Carcinogenesis by Cigarette Smoke and Its Constituents: Nishikawa, A.
  • Nicotine and Cancer: Wu, W.K.K.
  • Wong, H.P.S.
  • Yu, L.
  • Cho, C.H.
  • Phytochemicals in the Prevention of Lung Cancer Induced by Tobacco Carcinogens: Chung, F.-L.
  • Mi, L.
  • Prevention of Tobacco Associated Morbidity and Mortality by a Vaccine against Nicotine: Cerny, E.H.
  • Franzini-Brunner, L.
  • Cerny, T..

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