Nuclear medicine in clinical diagnosis and treatment



Nuclear medicine in clinical diagnosis and treatment

edited by Sanjiv Sam Gambhir, P.J.Ell

Churchill Livingstone, 2004

3rd ed.

  • v.1
  • v.2

大学図書館所蔵 件 / 5



Previous ed.: 1998



This definitive and comprehensive 2 volume text-reference book is essential reading for those who are primarily involved in the practice of nuclear medicine. Over 180 contributors, all of them internationally recognized authorities, focus on current and newly available radionuclide techniques and directly apply them to clinical practice. Covering all of the major body systems and organs in which nuclear medicine procedures are used, the book takes a disease oriented approach and this new edition features the latest advances in diagnostic and therapeutic modalities used in the detection and treatment of cancer, heart disease, neurologic disorders, trauma and other common and less common diseases. There are major revisions/ new chapters in the areas of brain imaging, movement disorders, stroke, lymphoma therapy, bone density, non-neurologic drug discovery, molecular imaging, cost/benefit analysis.Features over 4,400 high quality images depicting a full range of both common and rare diseases and abnormalities. Emphasizes how to perform and interpret a test rather than the technical aspects of the procedure, and focuses on how to solve the diagnostic problems that occur in day-to-day practice. Addresses practical considerations such as image interpretation, image optimization techniques, and pitfalls in image acquisition, and interpretation. Offers state-of-the art global perspectives from an international team of editors and authors.Provides completely revised and thoroughly up-to-date coverage in every chapter. Introduces a new co-editor-Dr Sam Gambhir, who provides new perspectives on the field's hottest developments. Presents expanded coverage of tumor diagnosis and therapy * cardiac nuclear imaging * and radionuclide imaging of neurologic and psychiatric disorders. Features brand-new chapters on lymphoma therapy * PET imaging * sentinel lymph node biopsy * gated SPECT * multi-modality imaging * molecular imaging * drug discovery * cost/benefit analysis * and bone density. Incorporates full-color images throughout the text.


Section 1: Nuclear medicine in tumor diagnosis and therapy Part A: Diagnosis1. Tumor-seeking radiopharmaceuticals: nature and mechanisms2 Radionuclide imaging of hepatic tumors3 PET in lymphoma and malignant melanoma4 Parathyroid imaging5 Adrenocortical scintigraphy6 Gallium scintigraphy in tumor diagnosis and management7 Thallium-201 chloride: a tumor imaging agent8 MIBG in the diagnosis of neuroendocrine tumors9 Peptide receptor scintigraphy in oncology10 The diagnostic role of radiolabeled antibodies in cancer11 Cancer cell biology basis for nuclear oncology12 Differentiated thyroid carcinoma13 Medullary thyroid cancer14 Breast scintigraphy15 Pediatric tumors16 Functional analysis of cancer therapy effects in other organs17 The use of intraoperative probes in surgical oncology18 The sentinel lymph node in surgical oncology19 FDG PET Imaging of Head and Neck Cancer20 External Beam Radiotherapy Treatment Planning with PET21 PET in aerodigestive tumors22 PET in gynecological tumors (breast, cervical and ovarian)23 Nuclear medicine imaging in pediatric oncology24 Positron Emission Tomography (PET) in genitourinary tumors: prostate, bladder, testicular and renal cancer25 Future clinical applications of PET (amino acid and nucleoside imaging)26 PET imaging of brain tumorsSection 1: Nuclear medicine in tumor diagnosis and therapy Part B: Radionuclide therapy27 Principles of radionuclide therapy28 Dosimetric and radiobiological considerations: The MIRD concept29 Dosimetric and radiobiological considerations: Patient-individual dosimetry30 Radioiodine therapy of the thyroid: Treatment of benign thyroid diseases31 Radioiodine therapy of the thyroid: Treatment of thyroid malignancies32 Phosphorus-32 therapy in myeloproliferative disorders33 Palliation of bone pain34 Radioimmunotherapy of hematologic neoplasms35 Radioimmunotherapy of solid tumors36 MIBG therapy37 Receptor-targeted radiopeptide therapy38 Use of radiolipiodol in the treatment of hepatic tumours39 Alternative approaches to targeting therapy40 New developments: Nuclear gene therapy41 Atlas 1: PET and PET/CT42 Atlas 2: SPET and SPET/CTSection 2: Nuclear medicine in disorders of bones and joints 43 Bone scintigraphy: the procedure and interpretation44 Evaluation of primary bone tumors45 The evaluation of malignancy: metastatic bone disease46 Assessment of infection47 Radionuclide assessment of the painful joint prosthesis48 Vascular manifestations49 Bone scintigraphy in trauma50 Bone scintigraphy in sports medicine51 Growth and metabolic disorders52 Arthritis: current status of scintigraphy and future trends53 Radiation synovectomySection 3: Quantitative studies of gastrointestinal function54 Salivary gland disorders55 Esophageal function (transport and motility)56 Gastric motility57 Intestines: evaluation of absorption58 Studies of small bowel and colonic transit59 Hepatobiliary function: biliary kinetics60 Scintigraphic measurement of hepatic functionSection 4: Nuclear medicine in acute care61 Nuclear cardiology and cardiac transplantation62 Cardiovascular conditions: venous thrombosis63 Pulmonary embolism64 Non-embolic disease of the lungs65 Gastrointestinal bleeding66 Cholescintigraphy67 Neonatal hyperbilirubinemia68 Nuclear medicine in acute care of neurological patients69 Radiolabeled agents for the localization of infection and inflammation70 Undiagnosed fever71 Inflammatory bowel disease72 Nuclear imaging in cardiovascular infection and cardiac transplant rejection73 The immunocompromised patientSection 5: Nuclear cardiology74 Radiopharmaceuticals for the study of the heart75 Radionuclide ventriculography and the assessment of impaired ventricular function76 Infarct avid imaging and myocardial perfusion scintigraphy techniques using single photon radiotracers77 Cardiac positron emission tomography78 Cardiac stress79 The detection of coronary artery disease80 Assessment of prognosis in patients with known or suspected coronary artery disease81 Assessment after myocardial revascularization82 Assessment of myocardial viability in dysfunctional myocardium83 Myocardial infarction: the assessment of thrombolysis84 Congenital heart disease85 Single-photon imaging of myocardial metabolism: the role of iodine 123 fatty acids and fluorine-18 deoxyglucose86 Clinical applications of PET87 Myocardial innervation: imaging and quantification88 Nuclear medicine techniques in the assessment of human thrombosis and atheromaSection 6: Nuclear medicine in neurological and psychiatric diagnosis 89 The blood-brain barrier90 Lipophilic tracers: the amines91 Lipophilic tracers for the study of regional cerebral blood flow92 Ligands for neuroreceptor imaging by positron or single photon emission tomography93 PET tracers for brain scanning94 Neuroactivation95 Image analysis in brain SPECT and PET96 SPECT brain imaging in cerebrovascular disease97 Nuclear medicine in the management of a patient with epilepsy98 Nuclear medicine and the management of patients with Parkinson's movement disorders99 Anxiety disorders and affective disorders100 Addictions101 The management of patients with schizophrenia102 PET and SPECT imaging in evaluating Alzheimer's disease and related dementias103 Nuclear medicine and drug studies in the brain104 Cerebrospinal fluid physiology, clearance flow studies and cerebrospinal fluid shunt studies105 Atlas 3: PET brain atlasSection 7: Nuclear medicine in renal disorders106 Overview of renal nuclear medicine107 Radiopharmaceuticals: their intrarenal handling and localization108 Dynamic static renal imaging109 Quantitative evaluation of clearance110 Measurement and interpretation of renal transit times111 The role of PET in renal nuclear medicine112 Renal infection113 Pediatric aspects of radionuclides in nephrourology114 Nuclear medicine in the clinical diagnosis and treatment of obstructive uropathy115 Vascular disorders, with emphasis on hypertension116 Renal failure117 Space-occupying lesions and trauma118 Renal transplant evaluation119 The genital tractSction 8: Basic sciences120 Fundamental molecular/cell biology121 Radioisotope production122 Radiochemistry123 Radiopharmacy124 Basic physics and detection of radiation125 Nuclear medicine imaging instrumentation126 Nuclear medicine computers: Basic principles127 Nuclear medicine computers: Applications128 Single photon emission computed tomography (SPECT)129 Positron emission tomography (PET)130 Primer on molecular imaging131 Radiation protection and dosimetry in clinical practice132 Clinical decision making: an introductory, quantitative approach to diagnostic investigations133 ecision analysis fundamentals

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    • 0443073120
    • 0443073120
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