Human genome epidemiology : building the evidence for using genetic information to improve health and prevent disease

著者

書誌事項

Human genome epidemiology : building the evidence for using genetic information to improve health and prevent disease

edited by Muin J. Khoury ... [et al.]

Oxford University Press, 2010

2nd ed

大学図書館所蔵 件 / 全5件

この図書・雑誌をさがす

注記

Includes bibliographical references and index

内容説明・目次

内容説明

The first edition of Human Genome Epidemiology, published in 2004, discussed how the epidemiologic approach provides an important scientific foundation for studying the continuum from gene discovery to the development, applications and evaluation of human genome information in improving health and preventing disease. Since that time, advances in human genomics have continued to occur at a breathtaking pace. With contributions from leaders in the field from around the world, this new edition is a fully updated look at the ways in which genetic factors in common diseases are studied. Methodologic developments in collection, analysis and synthesis of data, as well as issues surrounding specific applications of human genomic information for medicine and public health are all discussed. In addition, the book focuses on practical applications of human genome variation in clinical practice and disease prevention. Students, clinicians, public health professionals and policy makers will find the book a useful tool for understanding the rapidly evolving methods of the discovery and use of genetic information in medicine and public health in the 21st century.

目次

PART I: Fundamentals of human genome epidemiology revisited 1. Human genome epidemiology: The road map revisited Muin J. Khoury, Sara R. Bedrosian, Marta L. Gwinn, Julian P. T. Higgins, John P. A. Ioannidis, and Julian Little 2. Principles of analysis of germline genetics Jesus Gonzalez-Bosquet and Stephen Chanock 3. The public health genomics enterprise Philippa Brice and Ron Zimmern 4. Navigating the evolving knowledge of human genetic variation in health and disease Marta L. Gwinn and Wei Yu PART II: Methods and approaches for data collection, analysis and integration 5. The global emergence of epidemiological biobanks: Opportunities and challenges Paul Burton, Isabel Fortier, and Bartha Knoppers 6. Case-control and cohort studies in the age of genome-wide associations Teri Manolio 7. The emergence of networks in human genome epidemiology: Challenges and opportunities Daniela Seminara, Muin J. Khoury, Thomas R. O'Brien, Teri Manolio, Marta L. Gwinn, Julian Little, Julian P. T. Higgins, Jonine L. Bernstein, Paolo Boffetta, Melissa Bondy, Molly S. Bray, Paul E. Brenchley, Patricia A. Buf?er, Juan Pablo Casas, Anand P. Chokkalingam, John Danesh, George Davey Smith, Siobhan Dolan, Ross Duncan, Nelleke A. Gruis, Mia Hashibe, David Hunter, Marjo-Riitta Jarvelin, Beatrice Malmer, Demetrius M. Maraganore, Julia A. Newton-Bishop, Elio Riboli, Georgia Salanti, Emanuela Taioli, Nic Timpson, Andre G. Uitterlinden, Paolo Vineis, Nick Wareham, Deborah M. Winn, Ron Zimmern, and John P. A. Ioannidis 8. Design and analysis issues in genome-wide association studies Duncan Thomas 9. The challenge of assessing complex gene-gene and gene-environment interactions Peter Kraft and David Hunter 10. STrengthening the REporting of Genetic Association Studies (STREGA) - An extension of the STROBE statement Julian Little, Julian P.T. Higgins, John P.A. Ioannidis, David Moher, France Gagnon, Erik von Elm, Muin J. Khoury, Barbara Cohen, George Davey-Smith, Jeremy Grimshaw, Paul Scheet, Marta Gwinn, Robin E. Williamson, Guang Yong Zou, Kim Hutchings, Candice Y. Johnson, Valerie Tait, Miriam Wiens, Jean Golding, Cornelia van Duijn, John McLaughlin, Andrew Paterson, George Wells, Isabel Fortier, Matthew Freedman, Maja Zecevic, Richard King, Claire Infante-Rivard, Alex Stewart, and Nick Birkett 11. Integration of the evidence on gene-disease associations: Methods of HuGE reviews Julian P.T. Higgins and Julian Little 12. Genome-wide association studies, field synopses and the development of the knowledge base on genetic variation and human disease Muin J. Khoury, Lars Bertram, Paolo Boffetta, Adam S.Butterworth, Stephen J. Chanock, Siobhan M. Dolan, Isabel Fortier, Montserrat Garcia-Closas, Marta L. Gwinn, Julian P. T. Higgins, A. Cecile J.W. Janssens, James Ostell, Ryan P. Owen, Roberta A. Pagon, Timothy R. Rebbeck, Nathaniel Rothman, Jonine L. Bernstein , Paul R. Burton, Harry Campbell, Anand P. Chokkalingam, Helena Furberg, Julian Little, Thomas R. O'Brien, Daniela Seminara, Paolo Vineis, Deborah M. Winn, Wei Yu, and John P.A. Ioannidis PART III: Case studies: Cumulative assessment of the role of human genome variation in specific diseases 13. Colorectal cancer Harry Campbell, Steven Hawken, Evropi Theodoratou, Alex Demarsh, Kimberley Hutchings, Candice Y. Johnson, Lindsey Masson, Linda Sharp, Valerie Tait, Julian Little 14. Childhood leukemias Anand P. Chokkalingam and Patricia A. Buffler 15. Bladder cancer Jonine D. Figueroa, Montserrat Garcia-Closas, and Nathanial Rothman 16. Type 2 diabetes Mark McCarthy and Eleftheria Zeggini 17. Osteoporosis Andre G. Uitterlinden, Joyce B.J. van Meurs, and Fernando Rivadeneira 18. Preterm birth Siobhan M. Dolan 19. Coronary heart disease Adam S. Butterworth, Julian P.T. Higgins, Nadeem Sarwar, and John Danesh 20. Schizophrenia Lars Bertram PART IV: Applications of epidemiologic methods for using genetic information in medicine and public health 21. Mendelian randomization: The contribution to genetic epidemiology to elucidating environmentally modifiable causes of disease George Davey-Smith and Shah Ebrahim 22. Evaluation of predictive genetic tests for common diseases: Bridging epidemiological, clinical and public health measures A. Cecile J. W. Janssens, Marta Gwinn, and Muin J. Khoury 23. The Evaluation of Genomic Applications in Practice and Prevention (EGAPP) initiative: Methods of the EGAPP working group Steven M. Teutsch, Linda A. Bradley, Glenn E. Palomaki, James E. Haddow, Margaret Piper, Ned Calonge, W. David Dotson, Michael P. Douglas, and Alfred O. Berg 24. Rapid evidence-based reviews of genetic tests Jim M. Gudgeon, Glenn E. Palomaki, and Marc S. Williams 25. Role of social and behavioral research in assessing the utility of genetic information Saskia C. Sanderson , Christopher Wade, and Colleen M. McBride 26. Assessing the evidence for clinical utility in newborn screening Scott Grosse 27. The role of epidemiology in assessing the potential clinical impact of pharmacogenomics David L. Veenstra 28. The human epigenome and cancer Mukesh Verma 29. The use of family history in public health practice: the epidemiologic view Rodolfo Valdez, Muin J. Khoury, and Paula W. Yoon PART V: Case studies: Assessing the use of genetic information in practice for specific diseases 30. Cytochrome P450 testing in the treatment of depression Iris Grossman, Mugdha Thakur, and David B. Matchar 31. A rapid ACCE review of CYP2C9 and VKORC1 allele testing to inform warfarin dosing in adults at elevated risk for thrombotic events to avoid serious bleeding Monica R. McClain , Glenn E. Palomaki, Margaret Piper, and James E. Haddow 32. Hereditary hemochromatosis: Population screening for gene mutations Diana B. Petitti

「Nielsen BookData」 より

詳細情報

ページトップへ