Biochemistry
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Biochemistry
（USMLE road map）
McGraw-Hill, c2007
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Includes index
Description and Table of Contents
Description
Publisher's Note: Products purchased from Third Party sellers are not guaranteed by the publisher for quality, authenticity, or access to any online entitlements included with the product.
A premier tool for course review and USMLE preparation that distills the essential facts within biochemistry and helps students master the required content
You'll never find an easier, more efficient, and more focused way to ace biochemistry and biochemistry-related questions on the USMLE and course examinations than the USMLE Road Map. Designed to provide maximum learning in minimum time, this fully updated USMLE Road Map offers a concise, creative, and well-illustrated approach to mastering biochemistry.
Table of Contents
1. Physiological Chemistry and BondingA.Water as biochemical solventB.Hydrogen bondingC.pH and buffersD.Other non-covalent interactionsE.Fat-water interfaces2.Protein Structure and FunctionA.Amino acidsB.Primary structure-protein sequenceC.Secondary structures- -helix and -sheetD.Tertiary structure-domainsE.Quaternary structure-subunitsF.Fibrous proteins-collagen and elastinG.Globular proteins-myoglobin and hemoglobinH.Folding and chaperones3.Enzyme Structure and FunctionA.Types of enzymes-classificationB.Kinetics-Michaelis-Menten enzymesC.InhibitionD.Allosteric regulationE.Mechanisms-chymotrypsin and ribonuclease4.DNA Structure and FunctionA.Purine and pyrimidine basesB.The DNA moleculeC.Packaging into chromatinD.ReplicationE.Recombination and repair5.RNA Structure and FunctionA.RNA structures-mRNA, rRNA, tRNAB.TranscriptionC.SplicingD.Ribonucleoprotein complexes6.DNA and Chromosome AnalysisA.HybridizationB.Nucleic acid electrophoresisC.Northern and Southern blottingD.RFLP analysisE.Polymerase chain reactionF.Allele-specific oligonucleotidesG.Fluorescence in situ hybridization7.Control of Gene ExpressionA.The lac operonB.The Trp operonC.Eukaryotic promoters, enhancers and repressorsD.Transcription factorsE.Methylation and acetylation8. Protein Biosynthesis, degradation and traffickingA.TranslationB.Post-translational modificationC.SecretionD.Intracellular targetingE.Lysosomal degradationF.Proteosomal degradation9.Biological MembranesA.The lipid bilayerB.TransportC.Junctions and intercellular communication10.Cytoskeleton and Extracellular MatrixA.Microtubules and microfilamentsB.Integrins and focal adhesionsC.Extracellular matrix proteinsD.Proteoglycans and glycosaminoglycansE.Motility11.Overview of Metabolic RelationshipsA.Digestion of nutrientsB.Catabolism vs. anabolismC.CarbohydratesD.Lipids12.Carbohydrate MetabolismA.GlycolysisB.Anaerobic glycolysisC.Aerobic glycolysisD.Pentose Phosphate Pathway13.Hexose RegulationA.GluconeogenesisB.Glycogen biosynthesis and glycogenolysisC.Hexose metabolism14.Pyruvate OxidationA.Biosynthesis of Acetyl-CoAB.Steps of the TCA CycleC.Regulation of Pyruvate dehydrogenaseD.Regulation of the TCA cycle15.Oxidative PhosphorylationA.Transfer of electrons to Complex IB.Delivery of electrons through Complex IIC.Ubiquinone and common steps in electron transferD.Creation of a pH gradient during electron transferE.Utilization of the pH gradient to form ATPF.Inhibitors of ATP biosynthesis G.Stoichiometry of ATP biosynthesis16.Lipid MetabolismA.Fatty acid biosynthesisB.Fatty acid degradationC.Formation of triglyceridesD.Glycolipid biosynthesisE.Eicosanoid biosynthesisF.Cholesterol BiosynthesisG.Lipoproteins17.Amino Acid MetabolismA.Nitrogen metabolismB.Essential amino acidsC.Catabolism of amino acids D.Biosynthesis of amino acidsE.Biosynthesis of porphyrins18.Nucleic Acid MetabolismA.Biosynthesis of purinesB.Biosynthesis of pyrimidinesC.Biosynthesis of deoxynucleotidesD.Salvage pathways of bases E.Degradation of purinesF.Degradation of pyrimidines19.Nutritional BiochemistryA.General Nutritional RequirementsB.Vitamins1.Water-soluble2.Fat-solubleC.Essential inorganic nutrientsD.Essential amino acidsE.Essential lipids20.Receptors and Signal TransductionA.Overview of receptors and ligandsB.Types of receptorsC.Nuclear receptor superfamilyD.Membrane receptors1.G protein-coupled receptors2.Growth factor receptorsE.Nitric oxideF.Protein kinase AG.Protein kinase CH.Calcium-calmodulin signalingI.Kinase cascades21.Cancer BiologyA.Overview of cancer as a genetic diseaseB.DefinitionsC.Chemical carcinogenesisD.Radiation-induced DNA damage1.Ionizing radiation-x-rays, gamma rays2.Ultraviolet radiationE.Oncogene activationF.Tumor suppressorsG. Programmed cell death-apoptosis
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