Folate in health and disease

著者

    • Bailey, Lynn

書誌事項

Folate in health and disease

edited by Lynn B. Bailey

CRC Press, Taylor & Francis group, 2010

2nd ed

  • : hbk.

大学図書館所蔵 件 / 全4件

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注記

Includes bibliographical references and index

内容説明・目次

内容説明

During the fifteen years since the bestselling first edition of Folate in Health and Disease was published, there have been thousands of new research studies related to folate and its role in health and disease. The second edition of the book uniquely bridges the gap between basic science and public health/clinical medicine. Presents Groundbreaking Findings on Folate's Role in HealthNew insights related to folate chemistry, bioavailability, kinetics, metabolism, nutrient-gene, and nutrient-nutrient interaction are coupled with a public health/clinical medicine perspective of research findings targeted to birth defects, vascular and neurological diseases, and cancer. Epidemiological evidence is interpreted in tandem with new findings related to folate's mechanistic role in health maintenance and disease/birth defect prevention. Global recommendations for folate intake and a synopsis of folic acid fortification programs are featured. Folate acid intake and status in the U.S. are described in relation to the impact of fortification. A comprehensive critique of analytical techniques for folate analysis provides a valuable resource for future investigations as well as an interpretation of existing studies. Contributions from 50+ International ExpertsThis authoritative text covers: Folate-related genetic polymorphisms and birth defect risk Folic acid fortification programs and effects on NTDs Vitamin B12 and choline interactions with folate Alcohol's influence on folate status and methionine metabolism Clinical folate deficiency and assessment Folate intake recommendations globally; consumption and status in the U.S. Assembling more than 50 international experts working on the front lines of folate research, this standard-setting reference brings you up to speed on the explosion of information garnered from a wealth of new developments. It continues to be a must-have resource for investigators in both basic and applied research and scientists and nutritionists in academia, clinical medicine, and public health.

目次

Folate Chemistry and Metabolism. Folate Bioavailability. Folate Biochemical Pathways and Their Regulation. Genetic Variation: Effect on Folate Metabolism and Health. Folate in Pregnancy and Lactation. Folate Status and Birth Defect Risk: Epidemiological Perspective. Folate-Related Birth Defects: Embryonic Consequences of Abnormal Folate Transport and Metabolism. Folic Acid Fortification: Neural Tube Defect Risk Reduction-A Global Perspective. Folate and Cancer: Epidemiological Perspective. Folate and Carcinogenesis: Basic Mechanisms. Folate and Vascular Disease: Epidemiological Perspective. Folate and Vascular Disease: Basic Mechanisms. Folate and Neurological Function: Epidemiological Perspective. Folate and Neurological Disease: Basic Mechanisms. Folate-Vitamin B12 Interrelationships: Links to Disease Risk. Clinical Folate Deficiency. Influence of Alcohol on Folate Status and Methionine Metabolism in Relation to Alcoholic Liver Disease. Folate and Choline Inter-relationships: Metabolic and Potential Health Implications. Folate: Recommended Intakes, Consumption, and Status. Kinetics of Folate and One-Carbon Metabolism. Folate Analytical Methodology.

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