Origin of cancers
著者
書誌事項
Origin of cancers
(Cancer treatment and research, [154])
Springer, c2010
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注記
Includes bibliographical references and index
内容説明・目次
内容説明
Precis This book is a treatise about the origin of cancers. I would like to convince readers that the basic tenets of the theory of a stem-cell origin of cancers also constitute a unified theory of cancer. Stem-cell origin of normal (and cancer) cells: Vitruvian version Every truth passes through three stages before it is recognized. In the first it is ridiculed, in the second, it is opposed, in the third, it is regarded as self-evident. - Arthur Schopenhauer v vi Preface Every person has a unique story to tell. My story is about cancer. Cancer touches the lives of countless people. Often enough, it leaves indelible tracks. Many lives have been lost; others are forever changed. For those who confront this deadly scourge, there is a sense of urgency, if not of desperation. For those who face im- nent death, life becomes even more precious and carries a special meaning. As an oncologist, I am touched daily by cancer. I feel its inception, evolution, and aft- math. It seems as though we are fighting an incessant war against cancer at the front line in the trenches. This is my story about cancer. Some people are terrific storytellers. Others have incredible tales to tell.
目次
Introduction
Cancer myths
History of cancer
Origin of cancer
Stem cells
Stem cells and cancer
Cancer stem cells
Cancer niche
Ontogeny and oncology
Diagnosis and prognosis
Cancer targets
Heterogeneity of cancer
Metastasis
Cancer immunity
Drug resistance
Paradigm shifts
Experimental proof
Clinical implications
Curing cancer
Epilogue
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