A guide to human gene therapy
著者
書誌事項
A guide to human gene therapy
World Scientific, c2010
- : hbk
大学図書館所蔵 全4件
  青森
  岩手
  宮城
  秋田
  山形
  福島
  茨城
  栃木
  群馬
  埼玉
  千葉
  東京
  神奈川
  新潟
  富山
  石川
  福井
  山梨
  長野
  岐阜
  静岡
  愛知
  三重
  滋賀
  京都
  大阪
  兵庫
  奈良
  和歌山
  鳥取
  島根
  岡山
  広島
  山口
  徳島
  香川
  愛媛
  高知
  福岡
  佐賀
  長崎
  熊本
  大分
  宮崎
  鹿児島
  沖縄
  韓国
  中国
  タイ
  イギリス
  ドイツ
  スイス
  フランス
  ベルギー
  オランダ
  スウェーデン
  ノルウェー
  アメリカ
注記
Includes bibliographical references and index
内容説明・目次
内容説明
Ever since the birth of molecular biology, the tantalizing possibility of treating disease at its genetic roots has become increasingly feasible. Gene therapy - though still in its infancy - remains one of the hottest areas of research in medicine. Its approach utilizes a gene transfer vehicle ('vector') to deliver therapeutic DNA or RNA to cells of the body in order to rectify the defect that is causing the disease. Successful therapies have been reported in humans in recent years such as cures in boys with severe immune deficiencies. Moreover, gene therapy strategies are being adapted in numerous biomedical laboratories to obtain novel treatments for a variety of diseases and to study basic biological aspects of disease. Correction of disease in animal studies, is steadily gaining ground, highlighting the immense potential of gene therapy in the medical profession.This book will cover topics that are at the forefront of biomedical research such as RNA interference, viral and non-viral gene transfer systems, treatment of hematological diseases and disorders of the central nervous system. Leading experts on the respective vector or disease will contribute the individual chapters and explain cutting-edge technologies. It also gives a broad overview of the most important gene transfer vectors and most extensively studied target diseases. This comprehensive guide is therefore a must-read for anyone in the biotechnology, biomedical or medical industries seeking to further their knowledge in the area of human gene therapy.
目次
- Non-Viral Vectors (S Sullivan)
- Adenoviral Vectors (A Baker)
- Retroviral Vectors and Integration Analysis (C von Kalle)
- Lentiviral Vectors (T VandenDriessche & M Chuah)
- Herpes Virus Vectors (J Glorioso)
- Adeno-Associated Viral (AAV) Vectors (N Muzyczka)
- Regulatory RNAs (Ribozymes, RNAi and miRNA) (A Lewin)
- Integrating Vectors (Transposon, Phage Integrase) (M Calos)
- Gene Correction Strategies/Zinc Fingers (M Porteus)
- Gene Switches (P Moullier)
- Gene Therapy for Disorders of the CNS (D Young)
- Hemoglobinopathies (A Srivastava)
- Severe Immune Deficiencies (A Aiuti)
- Hemophilia (R Herzog)
- Obesity and Diabetes (S Zolotukhin & C Wasserfall)
- Musculoskeletal Disorders (S Takeda)
- Cancer Gene Therapy (K Weigel-Van Aiken)
- Autoimmune Disorders (P Robbins)
- Lysosomal Storage Diseases (C Mah)
- Retinal Diseases (B Hauswirth)
- Pulmonary Diseases (T Flotte)
- Cardiovascular Diseases (B Byrne).
「Nielsen BookData」 より