Epigenetics and cancer
著者
書誌事項
Epigenetics and cancer
(Advances in genetics / edited by E.W. Caspari and M. Demerec, v. 70-71)
Academic Press, an imprint of Elsevier, 2010
- pt. A
- pt. B
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内容説明・目次
- 巻冊次
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pt. B ISBN 9780123808646
内容説明
Genes interact with the environment, experience, and biology of the brain to shape an animal's behavior. This latest volume in Advances in Genetics, organized according to the most widely used model organisms, describes the latest genetic discoveries in relation to neural circuit development and activity.
目次
SECTION I. Epigenetic changes induced by environmental and dietary/lifestyle factors
Induction of epigenetic alterations by dietary and other environmental factors
John C. Mathers and Caroline Relton
Induction of epigenetic alterations by chronic inflammation
Toshikazu Ushijima
Exposure in utero and early-life exposure and epigenetic alterations
Kent L. Thornburg
Folate, one carbone metabolism & DNA methylation in cancer
Robyn Ward
SECTION II. Epigenetic biomarkers
Epigenetic biomarkers for cancer pathophysiology
Dajun Deng
Detection of epigenetic changes in body fluids
Triantafillos Liloglou
Epigenetic biomarkers for cancer risk assessment
Toshikazu Ushijima
SECTION III. Application of epigenetics in molecular epidemiology and epigenetic cancer prevention
Epigenetics in molecular epidemiology
Yasuhito Yuasa
Epigenetic cancer prevention
Jia Chen
SECTION IV. Epigenetic databases
Epigenetics databases and computational methodologies
Drs Mate Ongenaert
- 巻冊次
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pt. A ISBN 9780123808660
内容説明
Genes interact with the environment, experience, and biology of the brain to shape an animal's behavior. This latest volume in Advances in Genetics, organized according to the most widely used model organisms, describes the latest genetic discoveries in relation to neural circuit development and activity.
目次
Introduction, objectives of the book
Zdenko Herceg and Toshikazu Ushijima
Section I. Basic epigenetic mechanisms in the regulation of critical cellular processes
DNA methylation and cancer
Manel Esteller
Histone modifications and cancer
Zdenko Herceg
Epigenetics and miRNAs in human cancer
George A Calin
Interplay between different epigenetic mechanisms
Rabih Murr
Section II. Epigenetic events underlying biological phenomena
Genomic imprinting and cancer
Eamonn Maher
Epigenetic code and stem cells
Yasuhiro Yamada
Inheritance of epigenetic aberrations (constitutional epimutations) in cancer susceptibility
Megan Hitchins
Section III. Cancer epigenome
Cancer epigenome
Stephan Beck
Identification of driver methylation by epigenomic analysis
Gerd Pfeifer
Epigenetic driver of genetic alterations
Minoru Toyota
Section VI. Epigenetic therapy and epigenetic drugs
DNA demethylating agents and epigenetic therapy of cancer
Mani Samson and Zdenko Herceg
Histone modification therapy of cancer
Severio Minucci
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