The chemical components of tobacco and tobacco smoke

著者

    • Rodgman, Alan
    • Perfetti, Thomas Albert

書誌事項

The chemical components of tobacco and tobacco smoke

Alan Rodgman, Thomas A. Perfetti

CRC Press, c2009

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注記

Includes bibliographical references (p. 1261-1482) and index

収録内容

  • The hydrocarbons
  • Alcohols and phytosterols
  • Aldehydes and ketones
  • Carboxylic acids
  • The esters
  • The lactones
  • Anhydrides
  • Carbohydrates and their derivatives
  • Phenols and quinones
  • The ethers
  • Nitriles
  • Acyclic amines
  • Amides
  • Imides
  • N-nitrosamines
  • Nitroalkanes, nitroarenes, and nitrophenols
  • Nitrogen heterocyclic components
  • Miscellaneous components
  • Fixed and variable gases
  • Metallic and nonmetallic elements, isotopes, ions, and salts
  • Pesticides and growth regulators
  • Genes, nucleotides, and enzymes
  • "Hoffmann analytes"
  • Tobacco and/or tobacco smoke components used as tobacco ingredients
  • Pryolysis
  • Carcinogens, tumorigens, and mutagens vs. anticarcinogens, inhibitors, and antimutagens
  • Free radicals
  • Summary

内容説明・目次

内容説明

The Chemical Components of Tobacco and Tobacco Smoke chronicles the extraordinary progress made by scientists in the field of tobacco science, from its beginnings in the early 1800s to the present. This comprehensive text provides over 6000 references on more than 8400 components identified in tobacco and tobacco smoke. Authored by two longtime researchers in tobacco science, the book examines the isolation and characterization of each component. It explores developments in pertinent analytical technology and results of experimental studies on biological activity, toxicity, and tumorigenicity, including the inhibition of adverse biological activity of specific tobacco smoke component by another tobacco smoke component. The authors discuss the controversies over the extrapolation of the biological effect of a specific component administered individually by one route versus its biological effect when the component is in a highly complex mixture and is administered by a different route. They also cite studies in which cigarette design technologies were developed to control the per cigarette mainstream smoke yield of Federal Trade Commission-defined tar and one or more specific tobacco smoke components of concern. Through numerous references, this dynamic resource elucidates both the historical background of and recent studies in tobacco and tobacco smoke research. It furthers the knowledge base of components, arming scientists and public health officials worldwide with the most current information available. Authors Alan Rodgman and Thomas A. Perfetti have been jointly awarded the 2010 CORESTA (Cooperative Centre for Scientific Research Relative to Tobacco) Prize for their extensive work on documenting the vast literature on the chemical composition of tobacco and tobacco smoke.

目次

The Hydrocarbons The Alkanes The Alkenes and Alkynes The Alicyclic Hydrocarbons The Monocyclic Aromatic Hydrocarbons The Polycyclic Aromatic Hydrocarbons Alcohols and Phytosterols Alcohols Phytosterols Aldehydes and Ketones The Assertion of Aldehydes and Ketones as Ciliastatic Tobacco Smoke Components Ciliastasis Studies with Cigarette Smoke Condensate Fractions Ciliastasis Studies with Individual Cigarette Mainstream Smoke Components Nose Inhalation of Environmental Tobacco Smoke vs. Mouth Inhalation of Mainstream Smoke Carboxylic Acids The Carboxylic Acids The Amino Acids and Related Compounds The Esters The Lactones Anhydrides Carbohydrates and Their Derivatives Phenols and Quinones Phenols Quinones The Ethers Nitriles Acyclic Amines Amides Imides N-Nitrosamines Volatile N-Nitrosamines Nonvolatile N-Nitrosamines Tobacco-Specific N-Nitrosamines N-Nitrosamino Acids Tobacco-Specific N-Nitrosamines: An Exception among the Major MSS Toxicants Direct Transfer of TSNAs from Tobacco vs. Their Formation during the Smoking Process Infrequently Studied Tobacco and/or Smoke Secondary Amines and Their N-Nitrosamines Flue-Curing and Tobacco-Specific N-Nitrosamines Nitroalkanes, Nitroarenes, and Nitrophenols Nitrogen Heterocyclic Components Monocyclic Five-Membered N-Containing Ring Compounds Monocyclic Six-Membered N-Containing Ring Compounds Lactams Oxazoles and Oxazines Aza-Arenes N-Heterocyclic Amines Miscellaneous Components Sulfur-Containing Components Halogenated Components Fixed and Variable Gases Metallic and Nonmetallic Elements, Isotopes, Ions, and Salts Elements, Isotopes, and Ions in Plants Methods for the Detection and Identification of Metals, Ions, and Isotopes in Tobacco and Tobacco Smoke The Transference of Elements, Isotopes, and Ions from Tobacco to Tobacco Smoke Pesticides and Growth Regulators Synthetic Pesticides and Plant Growth Regulator Residues on Tobacco Naturally Occurring Plant Growth Regulators and Pesticides in Tobacco Transfer Rates of Pesticides and Plant Growth Regulators to Mainstream Smoke Decomposition Products of Agrochemicals in Mainstream Smoke Methods for Analysis of Pesticides and Plant Growth Regulators Residues of Synthetic Pesticides and Plant Growth Regulators Identified in Tobacco and Tobacco Smoke Genes, Nucleotides, and Enzymes Tobacco Genetics Genes, Nucleotides, and Enzymes Identified in Tobacco "Hoffmann Analytes" Tobacco and/or Tobacco Smoke Components Used as Tobacco Ingredients Pyrolysis Individual Tobacco Types Extracts from Tobacco Individual Tobacco Components Tobacco Additives Cigarette Construction Materials (Paper, Adhesives, etc.) Flavoring Ingredients Carcinogens, Tumorigens, and Mutagens vs. Inhibitors, Anticarcinogens, and Antimutagens Carcinogens, Tumorigens, and Mutagens Anticarcinogens, Inhibitors, and Antimutagens Alternate Exposures Free Radicals Introduction Analytical Methods for Determination of Free Radicals Free Radicals in Tobacco Smoke Historical Review of Free Radical Research on Cigarette Smoke Proposed Mechanisms for the Generation of Free Radicals in Mainstream Smoke Summary Bibliography Index

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