Engineering genetic circuits

Author(s)

    • Myers, Chris J.

Bibliographic Information

Engineering genetic circuits

Chris J. Myers

(Chapman and Hall/CRC mathematical & computational biology series / series editors Alison M. Etheridge ... [et al.])

CRC Press, c2010

Available at  / 3 libraries

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"A Chapman & Hall book"--Cover

Includes bibliographical references and index

Description and Table of Contents

Description

An Introduction to Systems Bioengineering Takes a Clear and Systematic Engineering Approach to Systems Biology Focusing on genetic regulatory networks, Engineering Genetic Circuits presents the modeling, analysis, and design methods for systems biology. It discusses how to examine experimental data to learn about mathematical models, develop efficient abstraction and simulation methods to analyze these models, and use analytical methods to guide the design of new circuits. After reviewing the basic molecular biology and biochemistry principles needed to understand genetic circuits, the book describes modern experimental techniques and methods for discovering genetic circuit models from the data generated by experiments. The next four chapters present state-of-the-art methods for analyzing these genetic circuit models. The final chapter explores how researchers are beginning to use analytical methods to design synthetic genetic circuits. This text clearly shows how the success of systems biology depends on collaborations between engineers and biologists. From biomolecular observations to mathematical models to circuit design, it provides essential information on genetic circuits and engineering techniques that can be used to study biological systems.

Table of Contents

An Engineer's Guide to Genetic Circuits. Learning Models. Differential Equation Analysis. Stochastic Analysis. Reaction-Based Abstraction. Logical Abstraction. Genetic Circuit Design. Solutions to Selected Problems. References. Glossary. Index.

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