Handbook on analyzing human genetic data : computational approaches and software

著者

    • Lin, Shili
    • Zhao, Hongyu

書誌事項

Handbook on analyzing human genetic data : computational approaches and software

Shili Lin, Hongyu Zhao, editors

Springer, c2010

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注記

Includes bibliographical references and index

内容説明・目次

内容説明

This handbook offers guidance on selections of appropriate computational methods and software packages for specific genetic problems. Coverage strikes a balance between methodological expositions and practical guidelines for software selections. Wherever possible, comparisons among competing methods and software are made to highlight the relative advantages and disadvantage of the approaches.

目次

Population Genetics.- Haplotype Structure.- Linkage Analysis of Qualitative Traits.- Linkage Analysis of Quantitative Traits.- Markov Chain Monte Carlo Linkage Analysis Methods.- Population-Based Association Studies.- Family-Based Association Studies.- Haplotype Association Analysis.- Multiple Comparisons/Testing Issues.- Estimating the Absolute Risk of Disease Associated with Identified Mutations.- Processing Large-Scale, High-Dimension Genetic and Gene Expression Data.

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