DNA : fingerprinting, sequencing and chips

著者

    • Ovesen, Kresten
    • Matthiesen, Ulrich

書誌事項

DNA : fingerprinting, sequencing and chips

Kresten Ovesen and Ulrich Matthiesen, editors

(DNA : properties and modifications, functions and interactions, recombination and applications series)

Nova Biomedical Books, c2009

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注記

Includes bibliographical references and index

内容説明・目次

内容説明

DNA (deoxyribonucleic acid) is the hereditary material in humans and almost all other organisms. DNA sequencing is a common and requisite practice for molecular biologists today working in all areas of biology, including microbiology. This book aims to provide clues for DNA sequencing projects directed to unsequenced organisms in which many transcripts wait to be discovered, either coding small RNAs or genes homologue to known genes coding for protein products. This book also looks at the adoption of the polymerase chain reaction (PCR) to generate DNA profiles from minute biological samples, and the use of mitochondrial DNA to obtain information from old bones and the applications of Y chromosomal polymorphisms in sexual assault cases. Present research focuses on genetic markers for external visible traits and on improving the utility of poor quality samples with degraded DNA. The other direction of forensic DNA research addresses the difficulty of obtaining a DNA profile in a degraded crime stain. The third topic covered in this book is DNA chips- a microchip that holds DNA probes that form half of the DNA double helix. This book examines the development of DNA chips, as the prototype for global technology genetics.

目次

  • Preface
  • Acquired Antibiotic Resistance in Starters and Probiotics Strains of Lactic Acid Bacteria and Bifidobacteria Species
  • Bacterial vectors in Dinoflagellate Ciguatoxin Production
  • Antibody variable-region sequencing for hybridoma authentication
  • DNA Sequencing: Methods, Strategies and Protocols
  • DNA Sequencing: Methods, Strategies and Protocols in Molecular Biology Research Horizons
  • RetroArray -- a comprehensive diagnostic DNA chip for rapid detection and identification of retroviruses, retroviral contaminants, and mistaken identity of cell lines
  • Biogenomic pathways in breast and ovarian malignancies: clinical and surgical workflow focused on tailoring procedures.
  • Microarray analysis of altered gene expression in the kidney of mice exposed to radiation
  • Methods of data analysis applied to sequentially accumulated gene signatures.
  • Application of Genomic Fingerprinting Methods for Molecular Characterization of Bioleaching Microorganisms
  • DNA Fingerprinting: Applications, Methods and Processes
  • SNPs, mini-STRs and Molecular Photofitting: Novel Directions for Forensic DNA Typing
  • Application of PCR-DGGE fingerprinting in molecular ecology of marine microbial symbionts
  • Index.

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