Drug transporters
Author(s)
Bibliographic Information
Drug transporters
(Handbook of experimental pharmacology, v. 201)
Springer Verlag, c2011
- : pbk
Available at 16 libraries
  Aomori
  Iwate
  Miyagi
  Akita
  Yamagata
  Fukushima
  Ibaraki
  Tochigi
  Gunma
  Saitama
  Chiba
  Tokyo
  Kanagawa
  Niigata
  Toyama
  Ishikawa
  Fukui
  Yamanashi
  Nagano
  Gifu
  Shizuoka
  Aichi
  Mie
  Shiga
  Kyoto
  Osaka
  Hyogo
  Nara
  Wakayama
  Tottori
  Shimane
  Okayama
  Hiroshima
  Yamaguchi
  Tokushima
  Kagawa
  Ehime
  Kochi
  Fukuoka
  Saga
  Nagasaki
  Kumamoto
  Oita
  Miyazaki
  Kagoshima
  Okinawa
  Korea
  China
  Thailand
  United Kingdom
  Germany
  Switzerland
  France
  Belgium
  Netherlands
  Sweden
  Norway
  United States of America
Note
Includes bibliographical references and index
Description and Table of Contents
Description
It is increasingly recognized that various transporter proteins are expressed throughout the body and determine absorption, tissue distribution, biliary and renal elimination of endogenous compounds and drugs and drug effects. This book will give an overview on the transporter families which are most important for drug therapy. Most chapters will focus on one transporter family highlighting tissue expression, substrates, inhibitors, knock-out mouse models and clinical studies.
Table of Contents
- From the contents.- Preface.- Organic anion transporting polypeptides (OATPs)
- In vitro and in vivo evidence for the importance of organic anion transporters (OATs) in drug therapy
- In vitro and in vivo evidence for the importance of organic cation transporters (OCTs, MATEs) in drug therapy
- Intestinal bile salt transporters (ASBT and OST alpha/beta)
- hepatic bile salt transporters (NTCP and BSEP)
- Importance of P-glycoprotein for drug-drug interactions
- Importance of the multidrug resistance protein (MRP) family for pathophysiology and drug therapy
- Importance of breast cancer resistance protein transporters (BCRP)
- Molecular mechanisms of drug transporters regulation
- In vivo probes of drug transport
by "Nielsen BookData"