Systemic lupus erythematosus
著者
書誌事項
Systemic lupus erythematosus
Academic Press is an imprint of Elsevier, c2011
5th ed
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注記
Previous ed.: c2004
Includes bibliographical references and index
内容説明・目次
内容説明
Systemic lupus erythematosus (S.L.E.), commonly called lupus, is a chronic autoimmune disorder that can affect virtually any organ of the body. In lupus, the body's immune system, which normally functions to protect against foreign invaders, becomes hyperactive, forming antibodies that attack normal tissues and organs, including the skin, joints, kidneys, brain, heart, lungs, and blood. Lupus is characterized by periods of illness, called flares, and periods of wellness, or remission.
Because its symptoms come and go and mimic those of other diseases, lupus is difficult to diagnose. There is no single laboratory test that can definitively prove that a person has the complex illness.
To date, lupus has no known cause or cure. Early detection and treatment is the key to a better health outcome and can usually lessen the progression and severity of the disease. Anti-inflammatory drugs, anti-malarials, and steroids (such as cortisone and others) are often used to treat lupus. Cytotoxic chemotherapies, similar to those used in the treatment of cancer, are also used to suppress the immune system in lupus patients.
A new edition of this established and well regarded reference which combines basic science with clinical science to provide a translational medicine model. Systemic Lupus Erythematosus is a useful reference for specialists in the diagnosis and management of patients with SLE, a tool for measurement of clinical activity for pharmaceutical development and basic research of the disease and a reference work for hospital libraries.
目次
Section I. Basis of Disease Pathogenesis 1. Genetics 2. Cellular Pathogenesis 3. Humoral Pathogenesis 4. Environmental Aspects of Pathogenesis
Section II. Clinical Aspects of Disease 1. The Clinical Presentation 2. Organ Systems
Section III. APLS (Antiphospholipid Syndrome) 1. Pathogenesis 2. Clinical
Section IV. Treatment of SLE
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