Pharmacology of 5-HT6 receptors
著者
書誌事項
Pharmacology of 5-HT6 receptors
(International review of neurobiology, v. 94,
Elsevier Academic Press, c2010-
- pt. 1
- pt. 2
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注記
Includes bibliographical references and index
内容説明・目次
- 巻冊次
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pt. 1 ISBN 9780123849762
内容説明
The serotonin 5-HT6 receptor represents a novel pharmacological target whose impact on physiopathology of CNS functions remains undetermined. Some receptor antagonists have been synthesized and they show a modulatory role in learning and memory processes and food intake. The pharmacology of 5-HT6 receptor agonists is still under evaluation. However, both 5-HT6 antagonists and agonists seem to exert potential antidepressant activity. Recently, a second messenger system has been discovered. 5-HT6 receptor function is becoming more and more intriguing. Thus, the aim of the present book is to try to clarify the pharmacology of 5-HT6 receptors.
目次
5-HT6 Medicinal Chemistry
Kevin G. Liu and Albert J. Robichaud
Patents
Nicolas Vincent Ruiz and Gloria Oranias
5-HT6 Receptor Charactertization
Teresa Riccioni
5-HT6 receptor signal transduction. Second Messenger Systems
Xavier Codony, Javier Burgueno, Maria Javier Ramirez, Jose Miguel Vela
Electrophysiology of 5-HT6 Receptors
Annalisa Tassone, Graziella Madeo, Giuseppe Sciamanna, Antonio Pisani, and Paola Bonsi
Genetic Variations and Association
Massimo Gennarelli and Annamaria Cattaneo
Pharmacokinetics of 5-HT6 Receptors Ligands
Angelo Mancinelli
- 巻冊次
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pt. 2 ISBN 9780123859020
内容説明
The serotonin 5-HT6 receptor represents a novel pharmacological target whose impact on physiopathology of CNS functions remains undetermined. Some receptor antagonists have been synthesized, and they show a modulatory role in learning and memory processes and food intake. The pharmacology of 5-HT6 receptor agonists is still under evaluation. However, both 5-HT6 antagonists and agonists seem to exert potential antidepressant activity. Recently, a second messenger system has been discovered. 5-HT6 receptor function is becoming more and more intriguing. Thus, the aim of the present book is to try to clarify the pharmacology of 5-HT6 receptors.
目次
The Central Role of 5-HT6 Receptors in Modulating Brain Neurochemistry Lee A Dawson
5-HT6 receptor memory and amnesia. Behavioral Pharmacology: Learning and Memory Processes Alfredo Meneses, Perez-Garcia G, Tellez R, Ponce-Lopez T and C Castillo
Behavioral Pharmacology: Potential Antidepressant and Anxiolytic Properties Anna Wesolowska, Magdalena Jastrzebska-Wiesek
The 5-Ht6 Receptor as a Target for Developing Novel Anti Obesity Drugs David Heal, Jane Gosden, and Sharon Smith
Behavioral and neurochemical pharmacology of 5-HT6 receptors related to reward and reinforcement. Gaetano Di Chiara, Valentina Valentini and Sandro Fenu
5-HT6 Receptor Ligands and their Antipsychotic Potential Jorn Arnt and Christina Kurre Olsen
5-HT6 Receptor Ligands as Antidementia Drugs Ellen Siobhan Mitchell
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