A color atlas of comparative pathology of pulmonary tuberculosis

著者

    • Leong, F. Joel W.-M
    • Dartois, Veronique
    • Dick, Thomas

書誌事項

A color atlas of comparative pathology of pulmonary tuberculosis

editors, Franz Joel Leong, Veronique Dartois, and Thomas Dick

CRC Press, 2011

  • pbk. : alk. paper

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注記

Includes bibliographical references and index

Summary: "Written by notable authorities from the several disciplines involved with tuberculosis research, this book is the first pictorial histopathology atlas with annotations on tuberculosis. The book's drug discovery and animal model perspective makes in applicative rather than academic and presents the material in a highly readable format. Each section will cover the manifestations of induced or acquired pulmonary tuberculosis in one of six animal species (models) - human, non-human primate, rabbit, guinea pig, rat, and mouse. It provides low, medium, and high power microscopy views of lung tissue in color to enhance the understanding of TB for newcomers and the senior tuberculosis researchers."--Provided by publisher

収録内容

  • (Publisher-supplied data) 01 Drug discovery for neglected diseases of the developing world 02 Tuberculosis biology and drug discovery 03 Immunopathology of TB disease across species 04 Anatomy and histology of human lung 05 Pathology of tuberculo

内容説明・目次

内容説明

An annual death toll of 2 million, coupled with rising drug resistance, highlights the need for the development of new drugs, better diagnostics, and a tuberculosis (TB) vaccine. Addressing these key issues, A Color Atlas of Comparative Pathology of Pulmonary Tuberculosis introduces TB histopathology to the non-histopathologists, students, scientists, and doctors working, learning, and teaching in the field of TB. It contains 100 color photographs and illustrations that bring clarity to the information presented. The atlas takes the unusual approach of covering multiple species histopathology, arguably the first and quite possibly the only resource to do so. It provides a simple, annotated, and visual presentation of the comparative histopathology of TB in human and animal models. The editors have compiled information that helps TB scientists to distinguish between the features of all major animal models available and to use them with their strengths and limitations in mind. The book provides guidance for selecting the best animal model(s) to answer specific questions and to test the efficacy of drug candidates.

目次

Introduction to Tuberculosis. Tuberculosis Drug Discovery and the Role of Animal Models. Basic Histology of Human Lung. Histopathological Manifestations of Pulmonary Tuberculosis in Humans. Pulmonary Tuberculosis in Monkey. Pulmonary Tuberculosis in Rabbit. Pulmonary Tuberculosis in Guinea Pig. Pulmonary Tuberculosis in Rat. Pulmonary Tuberculosis in Mouse.

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