Advances in TNF family research : proceedings of the 12th International TNF Conference, 2009

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書誌事項

Advances in TNF family research : proceedings of the 12th International TNF Conference, 2009

David Wallach, Andrew Kovalenko, Marc Feldmann, editors

(Advances in experimental medicine and biology, v. 691)

Springer, c2011

タイトル別名

Advances in tumor necrosis factor family research

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注記

A collection of essays by the speakers at the 12th Biennial International TNF Conference, held at San Lorenzo del Escorial, Spain, April 2009

Includes bibliographical references and index

収録内容

  • Roles of the TNF family in tissue homeostasis and normal development
  • Novel aspects of signaling activation by the TNF family : novel aspects of the functions of the TRAFs and cIAPs
  • Novel aspects of signaling activation by the TNF : ubiquitin modification of signaling proteins
  • Novel aspects of signaling activation by the TNF family : TNF signaling and gene regulatory networks
  • Roles of the TNF family in infectous diseases and interrelationship of the TNF family and pattern recognition receptor signaling : roles of the TNF family in infectious diseases
  • Roles of the TNF family in infectious diseases and interrelationship of the TNF family and pattern recognition receptor signaling : interrelationship of the TNF family and pattern recognition receptor signaling
  • Novel aspects of immune regulation by the TNF family
  • Control of lymphocyte function and repertoire by theTNF family
  • Advances in applying our knowledge to therapy : mechanisms of pathological and therapeutic effects of the TNF family
  • Advances in applying our knowledge to therapy : rational design of new means for therapeutic modulation of function of the TNF family
  • Roles of the TNF family in neuronal development, function, and pathology
  • Cell death mechanisms controlled by the TNF family
  • Contributors to abstracts of talks and posters at the 12th TNF Conference
  • Abstracts of talks and posters presented at the 12th TNF Conference

内容説明・目次

内容説明

The biennial TNF-family conferences have been held over the past 20 years, from the time that TNF was cloned. These meetings have followed the enormous progress in this field. Much is now known about the members of the TNF ligand and receptor families, their signaling proteins, mechanisms of action and cellular functions. This volume is the proceedings of the 12th TNF International Conference, held in April 2009. This conference focuses on the physiological, pathophysiological, and medical significance of these important regulators. Sessions at the meeting specifically address their involvement in immunity, development, apoptosis, autoimmunity, cancer, and infection, the normal function and pathology of the neuronal system, as well as major unresolved questions about their mechanisms of action.

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