NF-κB in health and disease

著者

• Karin, Michael

書誌事項

NF-κB in health and disease

Michael Karin, editor

（Current topics in microbiology and immunology, 349）

Springer Berlin, c2011

タイトル別名

NF-kB in health and disease

注記

Includes bibliographical references and index

内容説明・目次

内容説明

Nearly 25 years of intensive research have uncovered many diverse functions for the dimeric transcription factor known as NF-kappaB (nuclear factor-kappaB). NF-kappaB affects most aspects of cellular physiology-from immunity and inflammation to apoptosis, cell survival, growth, and proliferation

目次

Preface.- Understanding the Logic of I B:NF- B Regulation in Structural Terms.- NF- B/Rel proteins and the humoral immune responses of Drosophila melanogaster.- Specialized chromatin patterns in the control of inflammatory gene expression.- IKK regulation and human genetics.- Control of NF- B activity by proteolysis.- NF- B and Innate Immunity.- NF- B and mucosal homeostasis.- IKK and NF- B mediated functions in carcinogenesis.- Macrophages and NF- B in Cancer.- NF-kappaB in liver cancer - the plot thickens.- NF-kappaB as a target for oncogenic viruses.- Inhibition of NF- B signaling as a strategy in disease therapy.- Subject index

「Nielsen BookData」 より

詳細情報

• NII書誌ID(NCID): BB06000354
• ISBN:
  • 9783642160165
• 出版国コード: gw
• タイトル言語コード: eng
• 本文言語コード: eng
• 出版地: Berlin
• ページ数/冊数: viii, 268 p.
• 大きさ: 25 cm
• 分類:
  • SG : 610
• 親書誌ID:
  • BA00773360