Mechanosensing biology
著者
書誌事項
Mechanosensing biology
Springer, c2011
大学図書館所蔵 全6件
  青森
  岩手
  宮城
  秋田
  山形
  福島
  茨城
  栃木
  群馬
  埼玉
  千葉
  東京
  神奈川
  新潟
  富山
  石川
  福井
  山梨
  長野
  岐阜
  静岡
  愛知
  三重
  滋賀
  京都
  大阪
  兵庫
  奈良
  和歌山
  鳥取
  島根
  岡山
  広島
  山口
  徳島
  香川
  愛媛
  高知
  福岡
  佐賀
  長崎
  熊本
  大分
  宮崎
  鹿児島
  沖縄
  韓国
  中国
  タイ
  イギリス
  ドイツ
  スイス
  フランス
  ベルギー
  オランダ
  スウェーデン
  ノルウェー
  アメリカ
内容説明・目次
内容説明
Mechanical stress is vital to the functioning of the body, especially for tissues such as bone, muscle, heart, and vessels. It is well known that astronauts and bedridden patients suffer muscle and bone loss from lack of use. Even the heart, in pumping blood, causes mechanical stress to itself and to vascular tissue. With the loss of mechanical stress, homeostasis becomes impaired and leads to pathological conditions such as osteopenia, muscle atrophy, and vascular tissue dysfunction. In elderly populations, such mechanical pathophysiology, as well as the mechanical activities of locomotor and cardiovascular systems, is important because skeletal and heart functions decline and cause diseases in other organs. In this monograph, mechanical stress is discussed by experts in the field with respect to molecular, cellular, and tissue aspects in relation to medicine. Covering topics such as gravity and tissues and disuse osteoporosis, the book provides the most up-to-date information on cutting-edge advancements in the field of mechanobiology and is a timely contribution to research into locomotor and circulatory diseases that are major problems in contemporary society.
目次
-Part I Cells and Signals. -1. Nanotechnology in Mechanobiology: Mechanical Manipulation of Cells and Organelle While Monitoring Intracellular Signaling. -2.Molecular Mechanisms Underlying Mechanosensing in Vascular Biology. 3.Mechanobiology During Vertebrate Organ Development.
-Part II Tissue and Gravity. -4. Mechanobiology in Skeletal Muscle: Conversion of Mechanical Information into Molecular Signal. -5. Mechanobiology in Space. -6. Mechanical Stress and Bone. -7. TRP Channels and Mechanical Signals.
-Part III Skeletal Response. -8. Osteoblast Biology and Mechanosensing. -9. Osteocytes in Mechanosensing: Insights from Mouse Models and Human Patients. -10. Osteocyte Mechanosensation and Transduction. -11. Mechanosensing and Signaling Crosstalks. -12.Osteoblast Development in Bone Loss Due to Skeletal Unloading.
-Part IV Bone Signaling. -13. Mechanosensing in Bone and the Role of Glutamate Signalling. -14. Osteoclast Biology and Mechanosensing
-Part III Skeletal Response. -8. Osteoblast Biology and Mechanosensing. -9. Osteocytes in Mechanosensing: Insights from Mouse Models and Human Patients. -10. Osteocyte Mechanosensation and Transduction. -11. Mechanosensing and Signaling Crosstalks. -12.Osteoblast Development in Bone Loss Due to Skeletal Unloading.
-Part IV Bone Signaling. -13. Mechanosensing in Bone and the Role of Glutamate Signalling. -14. Osteoclast Biology and Mechanosensing
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