The origins of organ transplantation : surgery and laboratory science, 1880-1930

書誌事項

The origins of organ transplantation : surgery and laboratory science, 1880-1930

Thomas Schlich

(Rochester studies in medical history)

University of Rochester Press, 2010

  • : hardcover

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注記

Includes bibliographical references and index

内容説明・目次

内容説明

This book investigates a crucial-but forgotten-episode in the history of medicine. In it, Thomas Schlich systematically documents and analyzes the earliest clinical and experimental organ transplant surgeries. In so doing he laysopen the historical origins of modern transplantation, offering a new and original analysis of its conceptual basis within a broader historical context. This first comprehensive account of the birth of modern transplant medicine examines how doctors and scientists between 1880 and 1930 developed the technology and rationale for performing surgical organ replacement within the epistemological and social context of experimental university medicine. Theclinical application of organ replacement, however, met with formidable obstacles even as the procedure became more widely recognized. Schlich highlights various attempts to overcome these obstacles, including immunological explanations and new technologies of immune suppression, and documents the changes in surgical technique and research standards that led to the temporary abandonment of organ transplantation by the 1930s. Thomas Schlich is professor and Canada Research Chair in the History of Medicine at McGill University.

目次

An ancient dream of mankind? What is special about organ transplantation? Before organ replacement: A natural history approach to disease The invention of organ transplantation Organotherapy and organ replacement Rise and decline of thyroid transplantation The discovery of a new organ: the parathyroid gland Laboratory and clinic: organ replacement for diabetes The many uses of the adrenal gland Reconstructing women: ovarian transplants Rejuvenating men: testicle transplants One principle, multiple applications: further organs From special case to prototype: the kidney Ethical problems with organ transplantation Laboratory and clinic: the epistemic and social context Methods of monitoring the success of transplants Disillusionment: The clinical failure of organ transplantation The strategy of technical perfection A new direction: transplant immunology Chance and necessity: a fresh start for organ transplantation

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