Animal models
著者
書誌事項
Animal models
（Handbook of laboratory animal science / edited by Jann Hau, Steven J. Schapiro, v. 2-3）
CRC Press, c2011-2014
3rd ed
- 2 : hardback
- 3
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注記
Includes bibliographical references and index
内容説明・目次
- 巻冊次
-
2 : hardback ISBN 9781420084573
内容説明
Biomedical research involving animals remains essential for the advancement of the medical, veterinary, agricultural, and biological sciences. Following in the footsteps of its predecessors, the Handbook of Laboratory Animal Science, Volume II, Third Edition: Animal Models explains in great detail the comparative considerations underlying the choice of animal species and strains in different research disciplines.
Efficient and humane experimental work with animals, in which subjects experience no avoidable pain and mental distress, requires skillful and conscientious staff. To this end, scientists apply the three R's: replacing experiments on live animals with alternative methods, reducing the number of animals necessary to obtain valid results within experiments, and refining techniques to minimize the discomfort experienced by the animal participants.
目次
Animal Models. Animal Models for Human Behavior. Animal Models for Psychological Disorders. Animal Models in Neuroscience. Induced Animal Models of Parkinson's Disease. Animal Models in Aging and Alzheimer's Disease. Animal Models in Pain Research. Animal Models in Pharmacology and Toxicology. Animal Models for Otolaryngological Disorders. Animal Models of Lung Physiology during Anesthesia. Animal Models of Female Reproduction and Fetal Growth and Development. Animal Models in Vaccinology. Animal Models in AIDS Research. Animal Models for the Study of Helicobacter Infection. Animal Models in Mycology. Animal Models in Biodefense Research. Animal Models in Oral Health Sciences. Animal Models of Hearing Loss and Tinnitus.
- 巻冊次
-
3 ISBN 9781466555129
内容説明
While replacing and reducing the use of laboratory animals are integral parts of the 3Rs-replace, reduce, refine-which form the cornerstones of laboratory animal science, biomedical research involving animals remains absolutely essential for the advancement of the medical, veterinary, agricultural, and biological sciences. Building upon the bestselling previous edition, the Handbook of Laboratory Animal Science, Volume III, Third Edition: Animal Models complements volumes I and II of the third edition by completing the task of providing a comprehensive overview of animal models in all biomedical disciplines.
The three Rs have been integrated throughout this handbook to promote efficient and humane experimental work with animals. Written by international experts, each chapter focuses on an important subdiscipline of laboratory animal science and can be used as a stand-alone text. This volume contains new chapters for six additional disease animal models: spinal cord injury, cardiovascular diseases, sudden infant death syndrome, developmental disorders, eye diseases, and human cancer. It also presents a new chapter on applying reduction and refinement to animal models.
This handbook can be used for undergraduate and postgraduate laboratory animal science courses, and as a handbook for scientists who work with animals in their research, for university veterinarians, for regulators, and for other specialists in laboratory animal science.
目次
Animal Models of Spinal Cord Injury. Animal Models for Tropical Parasitic Diseases. Animal models of cardiovascular disease. Animal Models of Sudden Infant Death Syndrome. More Animal Models of Developmental Processes and Developmental Disorders for Social Genomics and Beyond. Animal Models of Metabolic and Inflammatory Diseases. Animal Models for Eye Diseases. Animal Models of Human Cancer. Reduction and Refinement Applied to Animal Models. Index.
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