Structural biology using electrons and X-rays : an introduction for biologists

著者

    • Moody, Michael F., Dr

書誌事項

Structural biology using electrons and X-rays : an introduction for biologists

Michael F. Moody

Academic Press, 2011

大学図書館所蔵 件 / 全5件

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注記

Includes bibliographical references (p. 417-425) and index

内容説明・目次

内容説明

Structural Biology Using Electrons and X-Rays discusses the diffraction and image-based methods used for the determination of complex biological macromolecules. The book focuses on the Fourier transform theory, which is a mathematical function that is computed to transform signals between time and frequency domain. Composed of five parts, the book examines the development of nuclear magnetic resonance (NMR), which allows the calculation of the images of a certain protein. Parts 1 to 4 provide the basic information and the applications of Fourier transforms, as well as the different methods used for image processing using X-ray crystallography and the analysis of electron micrographs. Part 5 focuses entirely on the mathematical aspect of Fourier transforms. In addition, the book examines detailed structural analyses of a specimen's symmetry (i.e., crystals, helices, polyhedral viruses and asymmetrical particles). This book is intended for the biologist or biochemist who is interested in different methods and techniques for calculating the images of proteins using nuclear magnetic resonance (NMR). It is also suitable for readers without a background in physical chemistry or mathematics.

目次

Part I: Fourier Transforms 1. Overview 2. Correlations & Convolutions 3. Fourier Fundamentals 4. Digital Fourier Transforms 5. Filters 6. Two-Dimensional FTs Part II: Optics 7. Microscopy with Rays 8. Waves 9. Wave Imaging Part III: Further Mathematical Methods/General Aspects 10. Symmetry 11. Statistics & Matrices 12. The Third Dimension Part IV: Image Analysis/Structure Determination 13. Special Symmetries 14. Crystalline Sheets 15. Helices 16. Icosahedral Particles 17. Unsymmetrical ("Single") Particles 18. Distortion Correction 19. FT Mathematics 20. Elementary Matrices

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